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异烟酸

异烟酸结构式
异烟酸结构式
品牌特惠专场
常用名 异烟酸 英文名 Isonicotinic acid
CAS号 55-22-1 分子量 123.109
密度 1.3±0.1 g/cm3 沸点 396.0±15.0 °C at 760 mmHg
分子式 C6H5NO2 熔点 ≥300 °C(lit.)
MSDS 中文版 美版 闪点 193.3±20.4 °C
符号 GHS07
GHS07
信号词 Warning

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

J. Sci. Ind. Res. 65(10) , 808, (2006)

Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI types (hepatotoxic side effects) seen in the clinic can be tra...

Developing structure-activity relationships for the prediction of hepatotoxicity.

Chem. Res. Toxicol. 23 , 1215-22, (2010)

Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification o...

Efficient Light-Driven Water Oxidation Catalysis by Dinuclear Ruthenium Complexes.

ChemSusChem 8 , 3688-96, (2015)

Mastering the light-induced four-electron oxidation of water to molecular oxygen is a key step towards the achievement of overall water splitting to produce alternative solar fuels. In this work, we report two rugged molecular pyrazolate-based diruthenium com...

[Fe(CN)5(isoniazid)](3-): an iron isoniazid complex with redox behavior implicated in tuberculosis therapy.

J. Inorg. Biochem. 140 , 236-44, (2014)

Tuberculosis has re-emerged as a worldwide threat, which has motivated the development of new drugs. The antituberculosis complex Na3[Fe(CN)5(isoniazid)] (IQG607) in particular is of interest on account of its ability to overcome resistance. IQG607 has the po...

High-internal-phase-emulsion polymeric monolith coupled with liquid chromatography-electrospray tandem mass spectrometry for enrichment and sensitive detection of trace cytokinins in plant samples.

Anal. Bioanal. Chem 407 , 6071-9, (2015)

High-internal-phase-emulsion polymers (polyHIPEs) show great promise as solid-phase-extraction (SPE) materials because of the tremendous porosity and highly interconnected framework afforded by the high-internal-phase-emulsion (HIPE) technique. In this work, ...

Liquid-phase step-by-step growth of an iron cyanide coordination framework on LiCoO₂ particle surfaces.

Dalton Trans. 44 , 15279-85, (2015)

Surface modification of inorganic objects with metal-organic frameworks (MOFs) - organic-inorganic hybrid framework materials with infinite networks - opens wide windows for potential applications. In order to derive a target property, the key is the ability ...