O-(苯并三唑-1-基)-N,N,N',N'-四甲基脲四氟硼酸酯
O-(苯并三唑-1-基)-N,N,N',N'-四甲基脲四氟硼酸酯结构式
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常用名 | O-(苯并三唑-1-基)-N,N,N',N'-四甲基脲四氟硼酸酯 | 英文名 | TBTU |
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| CAS号 | 125700-67-6 | 分子量 | 321.082 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C11H16BF4N5O | 熔点 | 205 °C (dec.)(lit.) | |
| MSDS | 中文版 美版 | 闪点 | STABILITY | |
| 符号 |
GHS02, GHS07 |
信号词 | Danger |
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Novel polymyxin derivatives carrying only three positive charges are effective antibacterial agents.
Antimicrob. Agents Chemother. 52 , 3229-36, (2008) The lack of novel antibiotics against gram-negative bacteria has reinstated polymyxins as the drugs of last resort to treat serious infections caused by extremely multiresistant gram-negative organisms. However, polymyxins are nephrotoxic, and this feature ma... |
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S. Zimmer et al., C.H. Schneider and A.N. Eberle, eds.
Proc. 22nd Eur. Pept. Symp.: Peptides 1992 Leiden 1993, p. 393
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O-(BENZOTRIAZOL-1-YL)-N, N, N', N'-TETRAMETHYLURONIUM TETRAFLUOROBORATE (TBTU): A NEW REAGENT FOR THE CLEAVAGE OF TETRAHYDROPYRANYL, SILYL AND 4, 4'-D IMETHOXYTRITYL ETHERS. Ramasamy KS and Averett D.
Synlett 6 , 709-712, (1999)
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I. Abdelmoty
Lett. Pept. Sci. 1 , 57, (1994)
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Semiautomated T-bag peptide synthesis using 9-fluorenyl-methoxycarbonyl strategy and benzotriazol-1-yl-tetramethyl-uronium tetrafluoroborate activation.
Pept. Res. 4(2) , 88-94, (1991) Multiple peptide synthesis using the T-bag method is considerably facilitated using 9-fluorenyl-methoxycarbonyl strategy and benzotriazol-1-yl-tetramethyl-uronium tetrafluoroborate activation. Convenient protocols were achieved when semiautomation was applied... |
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Automated solid-phase peptide synthesis: use of 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate for coupling of tert-butyloxycarbonyl amino acids.
Anal. Biochem. 200(2) , 301-9, (1992) 2-(1H-Benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate (TBTU) has been adapted for use as a coupling reagent for tert-butyloxycarbonyl (Boc) amino acids in automated solid-phase peptide synthesis. When compared to the existing preformed symmetr... |