六氟磷酸苯并三唑-1-基-氧基三吡咯烷基磷
六氟磷酸苯并三唑-1-基-氧基三吡咯烷基磷结构式
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常用名 | 六氟磷酸苯并三唑-1-基-氧基三吡咯烷基磷 | 英文名 | PyBOP |
|---|---|---|---|---|
| CAS号 | 128625-52-5 | 分子量 | 520.39200 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C18H28F6N6OP2 | 熔点 | 154-156 °C (dec.)(lit.) | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
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Structural, nanomechanical, and computational characterization of D,L-cyclic peptide assemblies.
ACS Nano 9(3) , 3360-8, (2015) The rigid geometry and tunable chemistry of D,L-cyclic peptides makes them an intriguing building-block for the rational design of nano- and microscale hierarchically structured materials. Herein, we utilize a combination of electron microscopy, nanomechanica... |
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Parallel synthesis of cell-penetrating peptide conjugates of PMO toward exon skipping enhancement in Duchenne muscular dystrophy.
Nucleic Acid Ther. 25(1) , 1-10, (2015) We describe two new methods of parallel chemical synthesis of libraries of peptide conjugates of phosphorodiamidate morpholino oligonucleotide (PMO) cargoes on a scale suitable for cell screening prior to in vivo analysis for therapeutic development. The meth... |
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Bi-specific splice-switching PMO oligonucleotides conjugated via a single peptide active in a mouse model of Duchenne muscular dystrophy.
Nucleic Acids Res. 43(1) , 29-39, (2015) The potential for therapeutic application of splice-switching oligonucleotides (SSOs) to modulate pre-mRNA splicing is increasingly evident in a number of diseases. However, the primary drawback of this approach is poor cell and in vivo oligonucleotide uptake... |
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Targeted Herceptin-dextran iron oxide nanoparticles for noninvasive imaging of HER2/neu receptors using MRI.
J. Biol. Inorg. Chem. 14(2) , 253-60, (2009) A novel magnetic resonance imaging (MRI) contrast agent containing Herceptin is reported. The surfaces of superparamagnetic iron oxide nanoparticles were modified with dextran and conjugated with Herceptin (Herceptin-nanoparticles) to improve their dispersion... |
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Coupling strategies for the synthesis of Peptide-oligonucleotide conjugates for patterned synthetic biomineralization.
J. Nucleic Acids 2011 , 926595, (2011) This work describes preparation strategies for peptide-oligonucleotide conjugates that combine the self-assembling behavior of DNA oligonucleotides with the molecular recognition capabilities of peptides. The syntheses include a solution-phase fragment coupli... |
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Expanding on the purification methodology of polyethylene glycol (PEG) bound molecules: The synthesis of 3, 5-pyrazolidinediones. Zhao X-Y, et al.
Tetrahedron Lett. 39(46) , 8433-8436, (1998)
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PyBOP Tetrahedron Lett. 31(2) , 205-208, (1990)
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Chemical synthesis and NMR characterization of structured polyunsaturated triacylglycerols.
Chem. Phys. Lipids 139(2) , 125-36, (2006) The chemical synthesis of pure triacylglycerol (TAG) regioisomers, that contain long chain polyunsaturated fatty acids, such as arachidonic acid (AA) or docosahexaenoic acid (DHA), and saturated fatty acids, such as lauric acid (La) or palmitic acid (P), at d... |