1,8-萘磺内酰胺
1,8-萘磺内酰胺结构式
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常用名 | 1,8-萘磺内酰胺 | 英文名 | 2H-naphth[1,8-cd]isothiazole 1,1-dioxide |
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| CAS号 | 603-72-5 | 分子量 | 205.23300 | |
| 密度 | 1.492g/cm3 | 沸点 | 442.2ºC at 760 mmHg | |
| 分子式 | C10H7NO2S | 熔点 | 173-175ºC(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 221.2ºC |
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Synthesis and activity of 2-(sulfonamido)methyl-carbapenems: discovery of a novel, anti-MRSA 1,8-naphthosultam pharmacophore.
Bioorg. Med. Chem. Lett. 9(5) , 673-8, (1999) A series of 1beta-methyl carbapenems substituted at the 2-position with lipophilic, acyclic and cyclic (sulfonamido)methyl groups was prepared and evaluated for activity against resistant gram-positive bacteria. From these studies, the 1,8-naphthosultamyl gro... |
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