2H-naphth[1,8-cd]isothiazole 1,1-dioxide
![2H-naphth[1,8-cd]isothiazole 1,1-dioxide Structure](https://image.chemsrc.com/caspic/455/603-72-5.png)
2H-naphth[1,8-cd]isothiazole 1,1-dioxide structure
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Common Name | 2H-naphth[1,8-cd]isothiazole 1,1-dioxide | ||
|---|---|---|---|---|
| CAS Number | 603-72-5 | Molecular Weight | 205.23300 | |
| Density | 1.492g/cm3 | Boiling Point | 442.2ºC at 760 mmHg | |
| Molecular Formula | C10H7NO2S | Melting Point | 173-175ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 221.2ºC | |
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Synthesis and activity of 2-(sulfonamido)methyl-carbapenems: discovery of a novel, anti-MRSA 1,8-naphthosultam pharmacophore.
Bioorg. Med. Chem. Lett. 9(5) , 673-8, (1999) A series of 1beta-methyl carbapenems substituted at the 2-position with lipophilic, acyclic and cyclic (sulfonamido)methyl groups was prepared and evaluated for activity against resistant gram-positive bacteria. From these studies, the 1,8-naphthosultamyl gro... |
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