![]() (S)-(+)-1,2,3,4-四氢-1-萘酚结构式
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常用名 | (S)-(+)-1,2,3,4-四氢-1-萘酚 | 英文名 | (S)-(+)-1,2,3,4-Tetrahydro-1-naphthol |
---|---|---|---|---|
CAS号 | 53732-47-1 | 分子量 | 148.202 | |
密度 | 1.1±0.1 g/cm3 | 沸点 | 254.8±0.0 °C at 760 mmHg | |
分子式 | C10H12O | 熔点 | 37-39ºC | |
MSDS | 中文版 美版 | 闪点 | 99.9±11.0 °C | |
符号 |
![]() GHS07 |
信号词 | Warning |
Stereochemical sensitivity of the human UDP-glucuronosyltransferases 2B7 and 2B17.
J. Med. Chem. 49 , 1818-27, (2006) A set of 28 enantiomers comprising rigid and flexible secondary alcohols was synthesized by the asymmetric Corey-Bakshi-Shibata reduction. The enantiomerically pure alcohols were subjected to enzymatic glucuronidation assays employing the human UDP-glucuronos... |
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Factorizing the role of a critical leucine residue in the binding of substrate to human 20alpha-hydroxysteroid dehydrogenase (AKR1C1): molecular modeling and kinetic studies of the Leu308Val mutant enzyme.
Bioorg. Med. Chem. Lett. 20 , 5274-6, (2010) A comparison of the structures and kinetic properties of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) and its mutant enzymes (Leu308Val and Leu308Ala) indicates that Leu308 is a selectivity determinant for substrate binding. While the Leu308Val mutatio... |
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