丹酰氯
丹酰氯结构式
|
常用名 | 丹酰氯 | 英文名 | Dansyl chloride |
|---|---|---|---|---|
| CAS号 | 605-65-2 | 分子量 | 269.747 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 371.3±22.0 °C at 760 mmHg | |
| 分子式 | C12H12ClNO2S | 熔点 | 72-74 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 178.4±22.3 °C | |
| 符号 |
GHS05 |
信号词 | Danger |
|
Self-immolative polycations as gene delivery vectors and prodrugs targeting polyamine metabolism in cancer.
Mol. Pharm. 12(2) , 332-41, (2015) Polycations are explored as carriers to deliver therapeutic nucleic acids. Polycations are conventionally pharmacological inert with the sole function of delivering therapeutic cargo. This study reports synthesis of a self-immolative polycation (DSS-BEN) base... |
|
|
The uptake of trehalose glycolipids by macrophages is independent of Mincle.
ChemBioChem. 16(4) , 683-93, (2015) Trehalose glycolipids play an important role in the pathogenesis of Mycobacterium tuberculosis and are used as adjuvants for vaccines; however, much still remains unanswered about the mechanisms through which these glycolipids exert their immunomodulatory pot... |
|
|
Sulfur amino acid metabolism in Zucker diabetic fatty rats.
Biochem. Pharmacol. 96 , 256-66, (2015) The present study was aimed to investigate the metabolomics of sulfur amino acids in Zucker diabetic fatty (ZDF) rats, an obese type 2 diabetic animal model. Plasma levels of total cysteine, homocysteine and methionine, but not glutathione (GSH) were markedly... |
|
|
Determination of bisphenol A, triclosan and their metabolites in human urine using isotope-dilution liquid chromatography-tandem mass spectrometry.
J. Chromatogr. A. 1348 , 97-104, (2014) Bisphenol A (BPA) and triclosan (TCS) are ubiquitous environmental phenols exhibiting endocrine disrupting activities that may be involved in various health disorders in humans. There is a need to measure separately free forms and conjugated metabolites becau... |
|
|
Polyamines in conventional and organic vegetables exposed to exogenous ethylene.
Food Chem. 188 , 218-24, (2015) Relationships between endogenous levels of polyamines by thin layer chromatography (TLC) and gas chromatography (GC), nitrate and response to the application of ethylene were established between organic and conventional vegetables (broccoli, collard greens, c... |
|
|
Development of a molecular recognition based approach for multi-residue extraction of estrogenic endocrine disruptors from biological fluids coupled to liquid chromatography-tandem mass spectrometry measurement.
Anal. Bioanal. Chem 407 , 8713-23, (2015) Multi-residue methods permitting the high-throughput and affordable simultaneous determination of an extended range of endocrine disrupting chemicals (EDCs) with reduced time and cost of analysis is of prime interest in order to characterize a whole set of bi... |
|
|
Evaluation of the sensitivity, responsiveness and reproducibility of primary rainbow trout hepatocyte vitellogenin expression as a screening assay for estrogen mimics.
Aquat. Toxicol. 159 , 233-44, (2015) Vitellogenin (Vtg) induction in primary fish hepatocytes has been proposed as an in vitro screening assay for ER agonists and antagonists, but has not yet been used extensively as a high-throughput screening tool due to poor reproducibility, sensitivity and o... |
|
|
A validated method for quantifying hypoglycin A in whole blood by UHPLC-HRMS/MS.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 978-979 , 70-7, (2015) Hypoglycin A (HGA) is the toxic principle in ackee (Blighia sapida Koenig), a nutritious and readily available fruit which is a staple of the Jamaican working-class and rural population. The aril of the unripe fruit has high concentrations of HGA, the cause o... |
|
|
Breaking the sensitivity limitations of cytochrome P450 oxidation product: dansyl chloride derivatisation of 4-OH mephenytoin, a CYP2C19 metabolite and its application to in vitro CYP inhibition assay.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 989 , 27-36, (2015) A rapid selective and sensitive liquid chromatography/tandem mass spectrometry (LC-MS/MS) method was developed for the quantitative determination of derivatised cytochrome P450-2C19 oxidation product (dansyl-4-OH mephenytoin) and its underivatised form (4-OH ... |
|
|
Determination and separation of bisphenol A, phthalate metabolites and structural isomers of parabens in human urine with conventional high-pressure liquid chromatography combined with electrospray ionisation tandem mass spectrometry.
Anal. Bioanal. Chem 407(9) , 2509-18, (2015) Phthalates, bisphenol A (BPA) and parabens (PBs), organic chemicals widely used in everyday products, are considered to be endocrine disruptors. We propose a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the determination of seven phtha... |