舒芬太尼
一般危化品
舒芬太尼结构式
|
常用名 | 舒芬太尼 | 英文名 | sufentanil |
|---|---|---|---|---|
| CAS号 | 56030-54-7 | 分子量 | 386.55100 | |
| 密度 | 1.132g/cm3 | 沸点 | 493.1ºC at 760mmHg | |
| 分子式 | C22H30N2O2S | 熔点 | 96.6ºC | |
| MSDS | N/A | 闪点 | 252ºC | |
| 符号 |
GHS02, GHS06, GHS08 |
信号词 | Danger |
|
Influence of intensive care treatment on the protein binding of sufentanil and hydromorphone during pain therapy in postoperative cardiac surgery patients.
Br. J. Anaesth. 113(4) , 677-87, (2014) Our objective was to evaluate the effect of intensive care treatment on the protein binding of sufentanil and hydromorphone in cardiac surgery patients during postoperative analgesia using a target-controlled infusion (TCI) and patient-controlled analgesia (P... |
|
|
Population pharmacokinetic modeling of hydromorphone in cardiac surgery patients during postoperative pain therapy.
Anesthesiology 120(2) , 378-91, (2014) Hydromorphone is a µ-selective opioid agonist used in postoperative pain therapy. This study aimed to evaluate the pharmacokinetics of hydromorphone in cardiac surgery patients during postoperative analgesia with target-controlled infusion and patient-control... |
|
|
Sufentanil citrate immobilization of Alaskan moose calves.
J. Wildl. Dis. 48(4) , 1088-91, (2012) Free-ranging Alaskan moose calves (Alces alces gigas) were immobilized with 0.12 mg/kg sufentanil (S; n=16), 0.12 mg/kg sufentanil plus 0.27 mg/kg xylazine (SX; n=11), or 0.007 mg/kg carfentanil plus 0.36 mg/kg xylazine (CX; n=13). Immobilants were antagonize... |
|
|
The practice of therapeutic hypothermia after cardiac arrest in France: a national survey.
PLoS ONE 7(9) , e45284, (2012) Cardiac arrest is a major health concern worldwide accounting for 375,000 cases per year in Europe with a survival rate of <10%. Therapeutic hypothermia has been shown to improve patients' neurological outcome and is recommended by scientific societies. Despi... |
|
|
Sufentanil-2-hydroxypropyl-β-cyclodextrin inclusion complex for pain treatment: physicochemical, cytotoxicity, and pharmacological evaluation.
J. Pharm. Sci. 101(10) , 3698-707, (2012) Sufentanil (SUF) is a synthetic analgesic opioid widely used for the management of acute and chronic pain. This drug was complexed with 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) and the physicochemical characterization, in vitro/ex vivo toxicity assays, and ph... |
|
|
The impact of intra-operative sufentanil dosing on post-operative pain, hyperalgesia and morphine consumption after cardiac surgery.
Eur. J. Pain 17(4) , 562-70, (2013) There is an ongoing debate whether opioids when used for intra-operative analgesia may enhance post-operative pain. We studied the effect of two different intra-operative dosings of sufentanil on post-operative morphine consumption, pain and hyperalgesia afte... |
|
|
Intranasal sufentanil for the treatment of acute pain in a winter resort clinic.
Am. J. Emerg. Med. 30(9) , 1817-21, (2012) Painful extremity injuries are common patient complaints in resort clinics, urgent care clinics, and emergency departments. We hypothesized that intranasal (IN) sufentanil could provide rapid, noninvasive, effective pain relief to patients presenting with acu... |
|
|
Avoiding bladder catheterisation in total knee arthroplasty: patient selection criteria and low-dose spinal anaesthesia.
Acta Anaesthesiol. Scand. 57(5) , 639-45, (2013) Bladder catheterisation may be inconvenient for patients, delay mobilisation and risk complications. We hypothesised that by excluding pre-operatively patients at high risk of post-operative urinary retention, the majority of patients could avoid perioperativ... |
|
|
Changes in total and unbound concentrations of sufentanil during target controlled infusion for cardiac surgery with cardiopulmonary bypass.
Br. J. Anaesth. 109(5) , 698-706, (2012) Target controlled infusion (TCI) with sufentanil is usually performed using the Gepts model, which was derived from patients undergoing general surgery. It is, however, known that pharmacokinetics of sufentanil can be changed during cardiopulmonary bypass (CP... |
|
|
Role of kinin B2 receptors in opioid-induced hyperalgesia in inflammatory pain in mice.
Biol. Chem. 394(3) , 361-8, (2013) Postoperative pain management is a clinical challenge that can be complicated by opioid-induced hyperalgesia (OIH). Kinin receptors could mediate both the acute and chronic phases of inflammation and pain. A few recent studies suggest that dynorphin A could m... |