5-氯-N-(6-苯基己基)-1-萘磺酰胺
5-氯-N-(6-苯基己基)-1-萘磺酰胺结构式
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常用名 | 5-氯-N-(6-苯基己基)-1-萘磺酰胺 | 英文名 | SC-9 |
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| CAS号 | 102649-78-5 | 分子量 | 401.94900 | |
| 密度 | 1.22g/cm3 | 沸点 | 577.5ºC at 760 mmHg | |
| 分子式 | C22H24ClNO2S | 熔点 | 75-76ºC | |
| MSDS | 中文版 美版 | 闪点 | 303.1ºC |
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Stimulation of choline transport in cultured cells induced by 12-O-tetradecanoylphorbol-13-acetate: one of the earliest phenomena induced by the tumor promoter.
Oncology 45(4) , 326-30, (1988) 12-O-tetradecanoylphorbol-13-acetate (TPA), a potent tumor promoter, stimulated membrane transport of choline in cultured cells. This is one of the earliest phenomena caused by tumor promoter. 4-O-methyl-TPA and mezerein showed similar stimulatory effects, bu... |
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N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide is one of a new class of activators for Ca2+-activated, phospholipid-dependent protein kinase.
Biochim. Biophys. Acta 889 , 236, (1986) N-(6-Phenylhexyl)-5-chloro-1-naphthalenesulfonamide (SC-9) activated Ca2+-activated, phospholipid-dependent protein kinase (protein kinase C). SC-9 acted as a substitute for phosphatidylserine, which is one of the endogenous factors in activating protein kina... |
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N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide, a novel activator of protein kinase C.
Biochemistry 25 , 4179, (1986) Naphthalenesulfonamide derivatives were used to study the mechanism of regulation of Ca2+-dependent smooth muscle myosin light chain phosphorylation catalyzed by Ca2+-activated, phospholipid-dependent protein kinase (protein kinase C) and myosin light chain k... |
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Evaluation of Salmonella live vaccines with chromosomal expression cassettes for translocated fusion proteins.
Vaccine 27 , 3780-7, (2009) Salmonella enterica is a versatile live carrier for the presentation of recombinant vaccine antigens. Fusion proteins of a type III secretion system effector and heterologous vaccine antigens can be translocated by live attenuated Salmonella strains and media... |
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Manipulation of phototransductive membrane turnover by crab photoreceptors in vitro: effects of two protein kinase activators, SC-9 and phorbol ester in the presence of a protein phosphatase inhibitor, okadaic acid.
J. Comp. Physiol. A. Neuroethol. Sens. Neural. Behav. Physiol. 170(2) , 189-99, (1992) 1. Retinae of crabs, Leptograpsus variegatus, held on a 12:12 h light-dark cycle were prepared for culture in vitro shortly before light-off. After an hour in darkness to permit the assembly of "night" rhabdoms, retinae were exposed to various combinations of... |
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Activation and inhibition of protein kinase C in cultured bovine parathyroid cells: effect on the release of C-terminal fragments of parathyroid hormone.
J. Bone Miner Res. 7(6) , 667-74, (1992) The response of the parathyroid gland to low Ca2+ may be mediated in part by protein kinase C (PKC). We assessed the effect of two PKC activators, SC-9 and SC-10, and one PKC inhibitor, H-7, on Ca(2+)-regulated PTH release and degradation in primary cultures ... |
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Regulatory effects of platelet-derived growth factor-AA homodimer on migration of vascular smooth muscle cells.
J. Biol. Chem. 267(32) , 22806-12, (1992) Migration of medial smooth muscle cells (SMC) into the intima is important in intimal thickening of atherosclerotic tissues. To study the functions of three isoforms of platelet-derived growth factor (PDGF) in atherosclerosis, we investigated their effects on... |
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Mechanism of the morphological changes induced by staurosporine in rat osteoblasts.
Calcif. Tissue Int. 61(1) , 68-73, (1997) Protein kinase C (PKC) plays an important role in the differentiation of cells, however, little is known about its relationship to bone metabolism. We have previously demonstrated that staurosporine concentration dependently transformed the cultured rat osteo... |
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Protein kinase C modulation of fibronectin matrix assembly.
J. Biol. Chem. 268(30) , 22277-80, (1993) Fibroblasts have cell surface sites that mediate the assembly of fibronectin (Fn) into the extracellular matrix. Treatment of fibroblasts with kinase inhibitors (ML-7, H7, HA1004, calphostin C, and staurosporine) resulted in the rapid decrease in the binding ... |
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Expression of the cystic fibrosis transmembrane conductance regulator gene can be regulated by protein kinase C.
J. Biol. Chem. 267(23) , 16056-60, (1992) Epithelial cells utilize at least two types of apical Cl- channels, the cAMP-activated cystic fibrosis transmembrane conductance regulator (CFTR) and the Ca2+/calmodulin-dependent Cl- channel. While phorbal ester (PMA) activates only CFTR-dependent Cl- secret... |