2-Methoxyidazoxan monohydrochloride
2-Methoxyidazoxan monohydrochloride结构式
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常用名 | 2-Methoxyidazoxan monohydrochloride | 英文名 | RX 821002 hydrochloride |
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| CAS号 | 109544-45-8 | 分子量 | 270.71200 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C12H15ClN2O3 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
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Role of the bed nucleus of the stria terminalis in the cardiovascular responses to acute restraint stress in rats.
Stress 12(3) , 268-78, (2009) The aim of this work was to test the hypothesis that the bed nucleus of the stria terminalis (BST) and noradrenergic neurotransmission therein mediate cardiovascular responses to acute restraint stress in rats. Bilateral microinjection of the non-specific syn... |
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Disruption of noradrenergic transmission and the behavioural response to a novel environment in NK1R-/- mice.
Eur. J. Neurosci. 25(4) , 1195-204, (2007) The behaviour of neurokinin-1-receptor gene knockout (NK1R-/-) mice, which lack functional, substance P-preferring receptors, resembles that of NK1R+/+ mice treated with an antidepressant. Because all antidepressants increase central monoamine transmission, w... |
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Adrenergic mechanisms of the Kölliker-Fuse/A7 area on the control of water and sodium intake.
Neuroscience 164(2) , 370-9, (2009) The blockade of serotoninergic receptors with methysergide or the activation of alpha(2)-adrenoceptors with moxonidine into the lateral parabrachial nucleus (LPBN) increases water and 0.3 M NaCl intake in rats treated with furosemide (FURO) combined with capt... |
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Insular cortex alpha1-adrenoceptors modulate the parasympathetic component of the baroreflex in unanesthetized rats.
Brain Res. 1295 , 119-26, (2009) The insular cortex (IC) has been reported to modulate the cardiac parasympathetic activity of the baroreflex in unanesthetized rats. However, which neurotransmitters are involved in this modulation is still unclear. In the present study, we evaluated the poss... |
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Alpha adrenergic modulation on effects of norepinephrine transporter inhibitor reboxetine in five-choice serial reaction time task.
J. Biomed. Sci. 16 , 72, (2009) The study examined the effects of a norepinephrine transporter (NET) inhibitor reboxetine (RBX) on an attentional performance test. Adult SD rats trained with five-choice serial reaction time task (5-CSRTT) were administered with RBX (0, 3.0 and 10 mg/kg) in ... |
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Lateral septal area α1- and α2-adrenoceptors differently modulate baroreflex activity in unanaesthetized rats.
Exp. Physiol. 97(9) , 1018-29, (2012) The lateral septal area (LSA) is a limbic structure involved in autonomic, neuroendocrine and behavioural responses. An inhibitory influence of the LSA on baroreflex activity has been reported; however, the local neurotransmitter involved in this modulation i... |
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Investigation of the distribution and function of alpha-adrenoceptors in the sheep isolated internal anal sphincter.
Br. J. Pharmacol. 160(7) , 1727-40, (2010) We have investigated the distribution of alpha-adrenoceptors in sheep internal anal sphincter (IAS), as a model for the human tissue, and evaluated various imidazoline derivatives for potential treatment of faecal incontinence.Saturation and competition bindi... |
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Inhibition of sodium appetite by lipopolysaccharide: involvement of alpha2-adrenoceptors.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 301(1) , R185-92, (2011) Lipopolysaccharide (LPS), an endotoxin from the wall of Escherichia coli, produces a general behavioral inhibition and affects several aspects of fluid-electrolyte balance. LPS inhibits thirst; however, it is not clear if it also inhibits sodium appetite. The... |
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Dopamine binds to alpha(2)-adrenergic receptors in the song control system of zebra finches (Taeniopygia guttata).
J. Chem. Neuroanat. 35(2) , 202-15, (2008) A commonly held view is that dopamine exerts its effects via binding to D1- and D2-dopaminergic receptors. However, recent data have emerged supporting the existence of a direct interaction of dopamine with adrenergic but this interaction has been poorly inve... |
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Differential effects of neonatal norepinephrine lesions on immediate early gene expression in developing and adult rat brain.
Neuroscience 157(4) , 821-32, (2008) Activity regulated cytoskeletal protein (Arc), c-fos and zif268 are immediate early genes (IEGs) important for adult brain plasticity. We examined developmental expression of these IEGs and the effect of neonatal noradrenergic lesion on their expression in de... |