3,3'-Difluorobenzaldazine
3,3'-Difluorobenzaldazine结构式
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常用名 | 3,3'-Difluorobenzaldazine | 英文名 | DFB |
|---|---|---|---|---|
| CAS号 | 15332-10-2 | 分子量 | 244.23900 | |
| 密度 | 1.12g/cm3 | 沸点 | 326.6ºC at 760mmHg | |
| 分子式 | C14H10F2N2 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 151.3ºC | |
| 符号 |
GHS07, GHS09 |
信号词 | Warning |
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A novel safety assessment strategy applied to non-selective extracts.
Food Chem. Toxicol. 80 , 163-81, (2015) A main challenge in food safety research is to demonstrate that processing of foodstuffs does not lead to the formation of substances for which the safety upon consumption might be questioned. This is especially so since food is a complex matrix in which the ... |
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Metabotropic glutamate receptor 5 positive allosteric modulators are neuroprotective in a mouse model of Huntington's disease.
Br. J. Pharmacol. 169 , 909-21, (2013) Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by a polyglutamine expansion in the huntingtin protein. We have previously demonstrated that the cell signalling of the metabotropic glutamate receptor 5 (mGluR5) is altered ... |
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A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5.
Mol. Pharmacol. 64 , 731-740, (2003) We have identified a family of highly selective allosteric modulators of the group I metabotropic glutamate receptor subtype 5 (mGluR5). This family of closely related analogs exerts a spectrum of effects, ranging from positive to negative allosteric modulati... |
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Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors.
Proc. Natl. Acad. Sci. U. S. A. 101 , 378-383, (2004) Although agonists bind directly in the heptahelical domain (HD) of most class-I rhodopsin-like G protein coupled receptors (GPCRs), class-III agonists bind in the extracellular domain of their receptors. Indeed, the latter possess a large extracellular domain... |
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Iron deprivation in Synechocystis: inference of pathways, non-coding RNAs, and regulatory elements from comprehensive expression profiling.
G3 (Bethesda) 2 , 1475-95, (2012) Iron is an essential cofactor in many metabolic reactions. Mechanisms controlling iron homeostasis need to respond rapidly to changes in extracellular conditions, but they must also keep the concentration of intracellular iron under strict control to avoid th... |
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Iron limitation modulates ocean acidification effects on southern ocean phytoplankton communities.
PLoS ONE 8 , e79890, (2013) The potential interactive effects of iron (Fe) limitation and Ocean Acidification in the Southern Ocean (SO) are largely unknown. Here we present results of a long-term incubation experiment investigating the combined effects of CO2 and Fe availability on nat... |
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Molecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP).
PLoS ONE 6 , e14757, (2011) Picropodophyllin (PPP) is a promising novel anti-neoplastic agent that efficiently kills tumor cells in vitro and causes tumor regression and increased survival in vivo. We have previously reported that PPP treatment induced moderate tolerance in two out of 1... |
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Oscillatory Dynamics and In Vivo Photoacoustic Imaging Performance of Plasmonic Nanoparticle-Coated Microbubbles.
Small 11 , 3066-77, (2015) Microbubbles bearing plasmonic nanoparticles on their surface provide contrast enhancement for both photoacoustic and ultrasound imaging. In this work, the responses of microbubbles with surface-bound gold nanorods-termed AuMBs-to nanosecond pulsed laser exci... |