富马酸伊布利特
富马酸伊布利特结构式
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常用名 | 富马酸伊布利特 | 英文名 | Ibutilide fumarate |
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| CAS号 | 122647-32-9 | 分子量 | 442.61 | |
| 密度 | N/A | 沸点 | 522.4ºC at 760 mmHg | |
| 分子式 | C22H38N2O5S | 熔点 | 112-117?C | |
| MSDS | 中文版 美版 | 闪点 | 269.7ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Efficacy and safety of ibutilide for chemical cardioversion of atrial fibrillation and atrial flutter in cancer patients.
Am. J. Med. Sci. 347(4) , 277-81, (2014) Atrial fibrillation and atrial flutter (AF/AFL) are the most common arrhythmias encountered in clinical practice. Rate versus rhythm control remains a difficult decision, especially in the acute setting. Ibutilide is a class III antiarrhythmic indicated for p... |
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Brugada syndrome masked by ibutilide treatment in a patient with atrial flutter.
Cardiology 122(2) , 89-92, (2012) We present a case of Brugada syndrome in a young patient whose typical ECG pattern was 'masked' after ibutilide was administered for atrial flutter cardioversion. Ibutilide, a class III antiarrhythmic agent used for the treatment of atrial fibrillation and fl... |
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Effects of ibutilide on canine cardiac pacing threshold and on induction rates of atrial fibrillation.
Cell Biochem. Biophys. 64(3) , 197-203, (2012) This study aims to observe the effects of ibutilide on canine cardiac pacing threshold and on induction rates of atrial fibrillation. Eighteen mongrel dogs were anesthetized and administrated with ibutilide. The pacing thresholds and induction rates of atrial... |
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Effect of ibutilide on the canine cardiac conduction system.
Cell Biochem. Biophys. 64(2) , 161-8, (2012) The objective of the study was to evaluate the effect of ibutilide on canine cardiac sinoatrial and atrioventricular nodes (AVNs). For this purpose, 18 mongrel dogs were injected intravenously with ibutilide and the changes in heart rate, sinus node recovery ... |
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Effects of ibutilide on inhibiting heart rate and rapidly terminating atrial flutter in canine.
Cell Biochem. Biophys. 59(3) , 153-8, (2011) Ibutilide is a newer class-III antiarrhythmic agent approved for clinical use. We sought to investigate its electrophysiological effects in canines and also the underlying mechanism of conversion of atrial flutter (AFL). For this purpose, 15 male mongrel dogs... |
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Ibutilide decreases defibrillation threshold by the reduction of activation pattern complexity during ventricular fibrillation in canine hearts.
Chin. Med. J. 125(15) , 2701-7, (2012) Ibutilide has been commonly used for pharmacologic cardioversion of atrial fibrillation and flutter in clinical settings. The objective of this study was to investigate the effects of ibutilide on the defibrillation threshold (DFT), restitution properties, di... |
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2:1 left to right interatrial block and other effects of ibutilide during non-isthmus-dependent atrial flutter.
Pacing Clin. Electrophysiol. 32(10) , e11-3, (2009) The effects of ibutilide on non-isthmus-dependent atrial flutter (NIDAFL) and the left atrium are not completely known. We describe a case report of 2:1 left to right interatrial block as a result of ibutilide during NIDAFL. This is a 68-year-old man with his... |
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Single dose of ibutilide for conversion of persistent atrial fibrillation after radiofrequency ablation.
Chin. Med. J. 124(5) , 710-3, (2011) Patients with persistent or permanent atrial fibrillation (AF) often need direct current cardioversion after radiofrequency ablation. The aim of this study was to investigate the effectiveness and safety of ibutilide for cardioversion of persistent or permane... |
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Predicting the degree of drug-induced QT prolongation and the risk for torsades de pointes.
Heart Rhythm 8(10) , 1535-6, (2011)
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Atrial fibrillation: AVRO--were the results a surprise?
Nat. Rev. Cardiol. 8(4) , 188-90, (2011)
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