前往化源商城

MADAM二盐酸盐

MADAM二盐酸盐结构式
MADAM二盐酸盐结构式
品牌特惠专场
常用名 MADAM二盐酸盐 英文名 2-[2-[(dimethylamino)methyl]phenyl]sulfanyl-5-methylaniline,dihydrochloride
CAS号 411208-45-2 分子量 345.33000
密度 N/A 沸点 426.4ºC at 760 mmHg
分子式 C16H22Cl2N2S 熔点 N/A
MSDS 中文版 美版 闪点 211.7ºC
符号 GHS07
GHS07
信号词 Warning

Substituted diphenyl sulfides as selective serotonin transporter ligands: synthesis and in vitro evaluation.

J. Med. Chem. 45 , 1253-1258, (2002)

A series of diphenyl sulfide derivatives substituted at the 1-, 2'-, and 4'-positions has been synthesized and evaluated for their in vitro affinities at the dopamine, serotonin (SERT), and norepinephrine transporters. The examination of K(i) values revealed ...

Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity.

J. Pharmacol. Exp. Ther. 304 , 81-87, (2003)

Serotonin transporter has a key-role in regulation of serotoninergic function, and is involved in numerous neurodegenerative and psychiatric disorders. To obtain an efficient radioactive ligand allowing the study of this transporter in vitro and in vivo, we s...