(S)-(-)-3-(3-羟基苯基)-N-丙基哌啶盐酸盐
(S)-(-)-3-(3-羟基苯基)-N-丙基哌啶盐酸盐结构式
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常用名 | (S)-(-)-3-(3-羟基苯基)-N-丙基哌啶盐酸盐 | 英文名 | PRECLAMOL HYDROCHLORIDE |
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| CAS号 | 88768-67-6 | 分子量 | 255.78 | |
| 密度 | N/A | 沸点 | 342.2ºC at 760 mmHg | |
| 分子式 | C14H22ClNO | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 158ºC |
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Central dopamine receptor agonist and antagonist actions of the enantiomers of 3-PPP.
Psychopharmacology 81 , 89-99, (1983) The two enantiomers of the putative centrally acting dopamine (DA) autoreceptor agonist 3-(3-hydroxyphenyl)-N-n-propylpiperidine, 3-PPP (Hjorth et al. 1981), were pharmacologically evaluated. An extensive series of biochemical and behavioural experiments unex... |
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Dopamine receptor agonistic and antagonistic effects of 3-PPP enantiomers.
Psychopharmacology 81 , 199-207, (1983) The pharmacological profile of the enantiomers of the proposed selective dopamine (DA) autoreceptor agonist 3-PPP [3-(3-hydroxyphenyl)-N-n-propylpiperidine] has been studied. In vitro both enantiomers showed weak DA agonistic activity, and (--)-3-PPP some DA ... |
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(+)-[3H]3-(3-hydroxyphenyl)-N-(1-propyl)-piperidine binding to sigma receptors in mouse brain in vivo.
Eur. J. Pharmacol. 161 , 263-266, (1989) Binding of i.v. administered (+)-[3H]3-(3-hydroxyphenyl)-N-(1-propyl)piperidine ([3H]3-PPP) in the brain of intact mice is antagonized dose responsively by sigma receptor ligands. The correlation of potencies for inhibition of binding in vivo and in vitro ind... |