PRECLAMOL HYDROCHLORIDE

PRECLAMOL HYDROCHLORIDE Structure
PRECLAMOL HYDROCHLORIDE structure
Common Name PRECLAMOL HYDROCHLORIDE
CAS Number 88768-67-6 Molecular Weight 255.78
Density N/A Boiling Point 342.2ºC at 760 mmHg
Molecular Formula C14H22ClNO Melting Point N/A
MSDS Chinese USA Flash Point 158ºC

Central dopamine receptor agonist and antagonist actions of the enantiomers of 3-PPP.

Psychopharmacology 81 , 89-99, (1983)

The two enantiomers of the putative centrally acting dopamine (DA) autoreceptor agonist 3-(3-hydroxyphenyl)-N-n-propylpiperidine, 3-PPP (Hjorth et al. 1981), were pharmacologically evaluated. An extensive series of biochemical and behavioural experiments unex...

Dopamine receptor agonistic and antagonistic effects of 3-PPP enantiomers.

Psychopharmacology 81 , 199-207, (1983)

The pharmacological profile of the enantiomers of the proposed selective dopamine (DA) autoreceptor agonist 3-PPP [3-(3-hydroxyphenyl)-N-n-propylpiperidine] has been studied. In vitro both enantiomers showed weak DA agonistic activity, and (--)-3-PPP some DA ...

(+)-[3H]3-(3-hydroxyphenyl)-N-(1-propyl)-piperidine binding to sigma receptors in mouse brain in vivo.

Eur. J. Pharmacol. 161 , 263-266, (1989)

Binding of i.v. administered (+)-[3H]3-(3-hydroxyphenyl)-N-(1-propyl)piperidine ([3H]3-PPP) in the brain of intact mice is antagonized dose responsively by sigma receptor ligands. The correlation of potencies for inhibition of binding in vivo and in vitro ind...