2-氨基-5-甲基噻唑
2-氨基-5-甲基噻唑结构式
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常用名 | 2-氨基-5-甲基噻唑 | 英文名 | 2-Amino-5-methylthiazole |
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| CAS号 | 7305-71-7 | 分子量 | 114.17 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 232.5±9.0 °C at 760 mmHg | |
| 分子式 | C4H6N2S | 熔点 | 93-98 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 94.4±18.7 °C | |
| 符号 |
GHS07, GHS09 |
信号词 | Warning |
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Design, synthesis, and evaluation of potential inhibitors of nitric oxide synthase.
Bioorg. Med. Chem. 16 , 6193-206, (2008) Selective inhibitors of neuronal nitric oxide synthase (nNOS) were shown to protect brain and may be useful in the treatment of neurodegenerative diseases. In this context, our purpose has been to design and synthesize a new family of derivatives of thiadiazo... |
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Copper(II) Schiff base coordination compounds of dien with heterocyclic aldehydes and 2-amino-5-methyl-thiazole: synthesis, characterization, antiproliferative and antibacterial studies. Crystal structure of CudienOOCl2.
J. Inorg. Biochem. 98(8) , 1271-83, (2004) A new series of coordination compounds of the starting materials [Cu(dienX(2)Y(2))] and their adducts [Cu(dienXXY(2))(2a-5mt)] (where dien=diethylenetriamine, dienXX=Schiff bases of diethylenetriamine with 2-furaldehyde or 2-thiophene-carboxaldehyde, X=O, S, ... |
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Antiproliferative activity of mixed-ligand dien-Cu(II) complexes with thiazole, thiazoline and imidazole derivatives.
J. Inorg. Biochem. 88(1) , 25-36, (2002) The reaction of [Cu(dien)NO(3)]NO(3) with 2-amino-5-methylthiazole (2A5MT), 2-amino-2-thiazoline (2A-2Tzn), imidazole (im), N,N'-thiocarbonyldiimidazole (Tcdim), 2-aminothiazole (2AT) and 2-ethylimidazole (2Etim), gave a new series of mixed-ligand compounds o... |
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The unexpected formation of biologically active Cu(II) Schiff mono-base complexes with 2-thiophene-carboxaldehyde and dipropylenetriamine: crystal and molecular structure of CudptaSCl2.
J. Inorg. Biochem. 99(2) , 467-76, (2005) Two novel mononuclear Cu(II) coordination compounds of the type [Cu(dptaS)Cl(2)] and [Cu(dptaS)Br(2)] (dptaS=1,3-propanediamine, N(1)-[3-aminopropyl]-N(3)-[2-thienylmethylidene] or Schiff mono-base of dipropylenetriamine with 2-thiophene-carboxaldehyde) were ... |
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Evaluation of anti-inflammatory and antioxidant activities of copper (II) Schiff mono-base and copper(II) Schiff base coordination compounds of dien with heterocyclic aldehydes and 2-amino-5-methyl-thiazole.
J. Enzyme Inhib. Med. Chem. 23(6) , 1011-7, (2008) Highly reactive radicals are implicated in many pathological conditions. The quest for radical scavengers or antioxidants, spans the previous decades. A new series of complexes of the type [Cu (dien) (2a-2tzn) Y(2)] and [Cu (dienXXY(2)) (2a-5mt)] and of the t... |
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(Thermo)dynamic role of receptor flexibility, entropy, and motional correlation in protein-ligand binding.
ChemPhysChem 9(7) , 983-8, (2008) The binding of 2-amino-5-methylthiazole to the W191G cavity mutant of cytochrome c peroxidase is an ideal test case to investigate the entropic contribution to the binding free energy due to changes in receptor flexibility. The dynamic and thermodynamic role ... |
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Ratio derivative spectrophotometric method for the determination of some oxicams in presence of their alkaline degradation products. Taha EA, et al.
Sci. Pharm. 71(4) , 303-20, (2003)
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Synthesis and characterization of new chelating resin: adsorption study of copper (II) and chromium (III) ions. Saçmaci S, et al.
J. Macromol. Sci., Part A: Pure Appl. Chem. 47(6) , 552-557, (2010)
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