4-氟苯基甲基砜
4-氟苯基甲基砜结构式
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常用名 | 4-氟苯基甲基砜 | 英文名 | 4-Fluorophenyl methyl sulfone |
|---|---|---|---|---|
| CAS号 | 455-15-2 | 分子量 | 174.193 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 295.9±32.0 °C at 760 mmHg | |
| 分子式 | C7H7FO2S | 熔点 | 78-81 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 132.8±25.1 °C |
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Phenoxyphenyl sulfone N-formylhydroxylamines (retrohydroxamates) as potent, selective, orally bioavailable matrix metalloproteinase inhibitors.
J. Med. Chem. 45(1) , 219-32, (2002) A novel series of sulfone N-formylhydroxylamines (retrohydroxamates) have been investigated as matrix metalloproteinases (MMP) inhibitors. The substitution of the ether linkage of ABT-770 (5) with a sulfone group 13a led to a substantial increase in activity ... |
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