4-Fluorophenyl methyl sulfone
4-Fluorophenyl methyl sulfone structure
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Common Name | 4-Fluorophenyl methyl sulfone | ||
|---|---|---|---|---|
| CAS Number | 455-15-2 | Molecular Weight | 174.193 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 295.9±32.0 °C at 760 mmHg | |
| Molecular Formula | C7H7FO2S | Melting Point | 78-81 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 132.8±25.1 °C | |
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Phenoxyphenyl sulfone N-formylhydroxylamines (retrohydroxamates) as potent, selective, orally bioavailable matrix metalloproteinase inhibitors.
J. Med. Chem. 45(1) , 219-32, (2002) A novel series of sulfone N-formylhydroxylamines (retrohydroxamates) have been investigated as matrix metalloproteinases (MMP) inhibitors. The substitution of the ether linkage of ABT-770 (5) with a sulfone group 13a led to a substantial increase in activity ... |
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