α-Equilol
α-Equilol结构式
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常用名 | α-Equilol | 英文名 | estra-1,3,5(10),7-tetraene-3,17alpha-diol |
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| CAS号 | 651-55-8 | 分子量 | 270.36600 | |
| 密度 | 1.23g/cm3 | 沸点 | 457.798ºC at 760 mmHg | |
| 分子式 | C18H22O2 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | 217.155ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Comparison of the proliferative effects of estradiol and conjugated equine estrogens on human breast cancer cells and impact of continuous combined progestogen addition.
Climacteric 6(3) , 221-7, (2003) So far, most epidemiological studies investigating breast cancer risk and hormone replacement therapy have been conducted with conjugated equine estrogens (CEE). Recent trials indicate that the addition of progestogens may increase breast cancer risk. In the ... |
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Ozonation of a mixture of estrogens and progestins in aqueous solution: interpretation of experimental results by computational methods.
Chemosphere 89(11) , 1323-9, (2012) The degradation of the mixture of steroid hormones including seven estrogens (17α-estradiol, 17β-estradiol, 17α-dihydroequilin, 17α-ethinyl estradiol, estriol, estrone and equilin) and five progestins (levonorgestrel, gestodene, trimegestrone, medrogestone an... |
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Free synthetic and natural estrogen hormones in influent and effluent of three municipal wastewater treatment plants.
Water Environ. Res. 79(9) , 969-74, (2007) Three municipal wastewater treatment plants (WWTPs) in southeastern Pennsylvania were sampled to determine the presence and concentrations of 12 natural and synthetic estrogen hormones in the wastewater influent and effluent. The target estrogens were 17alpha... |
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Determination of 17 alpha-dihydroequilenin in rat, rabbit and monkey plasma by high-performance liquid chromatography with fluorimetric detection.
J. Chromatogr. B, Biomed. Appl. 676(1) , 69-75, (1996) A high-performance liquid chromatographic (HPLC) method with fluorescence detection for the determination of total (unconjugated and conjugated) 17 alpha-dihydroequilenin in male and female rat, female rabbit and male and female rhesus monkey plasma is descri... |
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Biologic effects of 17 alpha-dihydroequilin sulfate.
Fertil. Steril. 66(5) , 748-52, (1996) To determine the independent biologic effects of 17 alpha-dihydroequilin sulfate.Prospective randomized study.University of Southern California Medical Center.Twenty-one postmenopausal women, mean age 50 +/- 2 (+/-SEM) years, and mean body mass index 27 +/- 2... |
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Occurrence of estrogen hormones in biosolids, animal manure and mushroom compost.
Environ. Monit. Assess. 184(2) , 1197-205, (2012) The presence of natural estrogen hormones as trace concentrations in the environment has been reported by many researchers and is of growing concern due to its possible adverse effects on the ecosystem. In this study, municipal biosolids, poultry manure (PM) ... |
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17alpha-Dihydroequilenin increases hippocampal dendritic spine density of ovariectomized rats.
Brain Res. 758(1-2) , 241-4, (1997) The effects of estradiol and 17alpha-dihydroequilenin on the apical dendrite spine density of pyramidal cells of the CA1 region of rat hippocampus were compared. 17alpha-Dihydroequilenin was as effective as estradiol in increasing spine densities relative to ... |
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Investigations into the biosynthetic pathways for classical and ring B-unsaturated oestrogens in equine placental preparations and allantochorionic tissues.
J. Steroid Biochem. Mol. Biol. 82(4-5) , 401-11, (2002) In on-going studies of 'classical' and ring B-unsaturated oestrogens in equine pregnancy, the products of metabolism of [2,2,4,6,6-2H(5)]-testosterone and [16,16,17-2H(3)]-5,7-androstadiene-3 beta,17 beta-diol with equine placental subcellular preparations an... |
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B-ring unsaturated estrogens: biological evaluation of 17alpha-Dihydroequilein and novel B-Nor-6-thiaequilenins as tissue selective estrogens.
Bioorg. Med. Chem. Lett. 13(24) , 4281-4, (2003) The pharmacology and SAR of representative equine estogens is described. 17alpha-Dihydroequilenin was found to prevent bone loss after 5 weeks of oral administration to ovariectomized rats. The stereochemical significance of the D-ring and the C/D ring junctu... |
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Reversed-phase liquid chromatographic method for estrogen determination in equine biological samples.
J. Chromatogr. Sci. 39(9) , 385-7, (2001) Equine unsaturated estrogens are the main components of brand formulations indicated for hormonal replacement therapy in both hypogonadic and postmenopausal women. These hormones are produced by the fetoplacental unit during equine gestation. A method is desc... |