人参皂苷Rb3
人参皂苷Rb3结构式
|
常用名 | 人参皂苷Rb3 | 英文名 | Ginsenoside Rb3 |
|---|---|---|---|---|
| CAS号 | 68406-26-8 | 分子量 | 1079.269 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 1117.1±65.0 °C at 760 mmHg | |
| 分子式 | C53H90O22 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 629.4±34.3 °C |
|
[A quantitative method using one marker for simultaneous assay of ginsenosides in Panax ginseng and P. notoginseng].
Yao Xue Xue Bao 43(12) , 1211-6, (2008) Current quality control patterns are limited to industrial application, for most of the natural chemical reference substances are expensive and unavailable. Herein, a method, quantitative analysis of multi-components with single marker (QAMS), was established... |
|
|
Inhibition of NMDA receptors underlies the neuroprotective effect of ginsenoside Rb3.
Am. J. Chin. Med. 37(4) , 759-70, (2009) In order to investigate the mechanisms underlying the neuroprotective effect of ginsenoside Rb3, rat hippocampal neurons were primarily cultured, and exposed to 1 mM N-methyl-D-aspartate (NMDA), cell viability and lactate dehydrogenase leakage were measured. ... |
|
|
Ginsenoside Rb3 ameliorates myocardial ischemia-reperfusion injury in rats.
Pharm. Biol. 49(9) , 900-6, (2011) Panax ginseng C. A. Mey (Araliaceae) has been widely used in clinic for treatment of cardiovascular diseases in China. Ginsenoside Rb3 is the main chemical component of Panax ginseng.The aim of this study was to evaluate the effect of ginsenoside Rb3 on myoca... |
|
|
Microbial transformation of ginsenosides Rb1, Rb3 and Rc by Fusarium sacchari.
J. Appl. Microbiol. 109(3) , 792-8, (2010) This study examined the transformation pathways of ginsenosides G-Rb(1) , G-Rb(3) , and G-Rc by the fungus Fusarium sacchari.Ginsenosides G-Rb(1) , G-Rb(3) and G-Rc were isolated from leaves of Radix notoginseng, and their structural identification was confir... |
|
|
Inhibitory influence of ginsenoside Rb(3) on activation of strychnine-sensitive glycine receptors in hippocampal neurons of rat.
Brain Res. 1037(1-2) , 99-106, (2005) Whole-cell patch-clamp technique was used to investigate the effect of ginsenoside Rb(3) (Rb(3)), an active constituent of Panax ginseng, on glycine receptor activity in immature hippocampal neurons, which were dissociated acutely from hippocampal CA(1) area ... |
|
|
Anti-diabetic effect of ginsenoside Rb(3) in alloxan-induced diabetic mice.
Med. Chem. 8(5) , 934-41, (2012) As one of the main active component of protopanaxdiol type ginsenosides, ginsenoside Rb(3) is rarely reported in the treatment of diabetes. The anti-diabetic activity of ginsenoside Rb(3) was investigated in a model of alloxan-induced diabetic mice in the pre... |
|
|
Influences of ginsenosides Rb1, Rb2, and Rb3 on electric and contractile activities of normal and damaged cultured myocardiocytes.
Zhongguo Yao Li Xue Bao 13(5) , 403-6, (1992) Free radical damage to the cultured myocardiocytes of Wistar rat was induced by adding xanthine 0.42 mmol.L-1 and xanthine oxidase 5.3 nmol.L-1 to the culture medium. 30 micrograms.ml-1 of Rb1, Rb2 or Rb3 extracted from the leaf and stem of Panax ginseng C A ... |
|
|
Protective effects of ginsenoside Rb(3) on oxygen and glucose deprivation-induced ischemic injury in PC12 cells.
Acta Pharmacol. Sin. 31(3) , 273-80, (2010) To investigate the protective effects of ginsenoside Rb(3), a triterpenoid saponin isolated from the leaves of Panax notoginseng, on ischemic and reperfusion injury model of PC12 cells and elucidate the related mechanisms.PC12 cells exposed to oxygen and gluc... |
|
|
[Chemical constituents of flower-buds of Panax ginseng--isolation and identification of ginsenoside-Rb3 and ginsenoside-Rc].
Zhong Yao Tong Bao 9(4) , 172-3, (1984)
|
|
|
[Effects and mechanisms of ginsenoside Rb3 on glutamate excitotoxic injury in cultured neurons of rat hippocampus].
Zhongguo Ying Yong Sheng Li Xue Za Zhi 22(1) , 31-4, (2006) To observe protective effects of ginsenoside Rb3 on glutamate excitotoxic injury in cultured hippocampal neurons and involved mechanisms.On cultured rat hippocampal neurons treated with glutamate at toxic concentration, we made the following investigations: b... |