γ-分泌酶抑制剂
γ-分泌酶抑制剂结构式
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常用名 | γ-分泌酶抑制剂 | 英文名 | YO-01027 |
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| CAS号 | 209984-56-5 | 分子量 | 463.476 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 801.3±65.0 °C at 760 mmHg | |
| 分子式 | C26H23F2N3O3 | 熔点 | 257-259ºC | |
| MSDS | 中文版 美版 | 闪点 | 438.4±34.3 °C |
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Notch inhibition allows oncogene-independent generation of iPS cells.
Nat. Chem. Biol. , doi:10.1038/nchembio.1552, (2014) The reprogramming of somatic cells to pluripotency using defined transcription factors holds great promise for biomedicine. However, human reprogramming remains inefficient and relies either on the use of the potentially dangerous oncogenes KLF4 and CMYC or t... |
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The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids.
Nat. Commun. 6 , 8989, (2015) The epithelial lining of the fallopian tube is of critical importance for human reproduction and has been implicated as a site of origin of high-grade serous ovarian cancer. Here we report on the establishment of long-term, stable 3D organoid cultures from hu... |
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