YO-01027

YO-01027 Structure
YO-01027 structure
Common Name YO-01027
CAS Number 209984-56-5 Molecular Weight 463.476
Density 1.4±0.1 g/cm3 Boiling Point 801.3±65.0 °C at 760 mmHg
Molecular Formula C26H23F2N3O3 Melting Point 257-259ºC
MSDS Chinese USA Flash Point 438.4±34.3 °C

Notch inhibition allows oncogene-independent generation of iPS cells.

Nat. Chem. Biol. , doi:10.1038/nchembio.1552, (2014)

The reprogramming of somatic cells to pluripotency using defined transcription factors holds great promise for biomedicine. However, human reprogramming remains inefficient and relies either on the use of the potentially dangerous oncogenes KLF4 and CMYC or t...

The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids.

Nat. Commun. 6 , 8989, (2015)

The epithelial lining of the fallopian tube is of critical importance for human reproduction and has been implicated as a site of origin of high-grade serous ovarian cancer. Here we report on the establishment of long-term, stable 3D organoid cultures from hu...