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4-(2H-四唑-5-基)苯硼酸

4-(2H-四唑-5-基)苯硼酸结构式
4-(2H-四唑-5-基)苯硼酸结构式
品牌特惠专场
常用名 4-(2H-四唑-5-基)苯硼酸 英文名 [4-(1H-Tetrazol-5-Yl)Phenyl]Boronic Acid
CAS号 179942-55-3 分子量 189.96700
密度 1.51g/cm3 沸点 480.3ºC at 760mmHg
分子式 C7H7BN4O2 熔点 N/A
MSDS 中文版 美版 闪点 244.2ºC

Discovery and SAR exploration of a novel series of imidazo[4,5-b]pyrazin-2-ones as potent and selective mTOR kinase inhibitors.

Bioorg. Med. Chem. Lett. 21 , 6793-6799, (2011)

We report here the discovery of a novel series of selective mTOR kinase inhibitors. A series of imidazo[4,5-b]pyrazin-2-ones, represented by screening hit 1, was developed into lead compounds with excellent mTOR potency and exquisite kinase selectivity. Poten...