![]() [4-(1H-Tetrazol-5-Yl)Phenyl]Boronic Acid structure
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Common Name | [4-(1H-Tetrazol-5-Yl)Phenyl]Boronic Acid | ||
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CAS Number | 179942-55-3 | Molecular Weight | 189.96700 | |
Density | 1.51g/cm3 | Boiling Point | 480.3ºC at 760mmHg | |
Molecular Formula | C7H7BN4O2 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 244.2ºC |
Discovery and SAR exploration of a novel series of imidazo[4,5-b]pyrazin-2-ones as potent and selective mTOR kinase inhibitors.
Bioorg. Med. Chem. Lett. 21 , 6793-6799, (2011) We report here the discovery of a novel series of selective mTOR kinase inhibitors. A series of imidazo[4,5-b]pyrazin-2-ones, represented by screening hit 1, was developed into lead compounds with excellent mTOR potency and exquisite kinase selectivity. Poten... |
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