2-噻吩乙醇
2-噻吩乙醇结构式
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常用名 | 2-噻吩乙醇 | 英文名 | 2-Thiopheneethanol |
|---|---|---|---|---|
| CAS号 | 5402-55-1 | 分子量 | 128.192 | |
| 密度 | 1.153 | 沸点 | 108 ºC (13 mmHg) | |
| 分子式 | C6H8OS | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 101 ºC |
|
Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides.
Bioorg. Med. Chem. 22(17) , 4968-97, (2014) TTK kinase was identified by in-house siRNA screen and pursued as a tractable, novel target for cancer treatment. A screening campaign and systematic optimization, supported by computer modeling led to an indazole core with key sulfamoylphenyl and acetamido m... |
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