2-Thiopheneethanol
2-Thiopheneethanol structure
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Common Name | 2-Thiopheneethanol | ||
|---|---|---|---|---|
| CAS Number | 5402-55-1 | Molecular Weight | 128.192 | |
| Density | 1.153 | Boiling Point | 108 ºC (13 mmHg) | |
| Molecular Formula | C6H8OS | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 101 ºC | |
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Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides.
Bioorg. Med. Chem. 22(17) , 4968-97, (2014) TTK kinase was identified by in-house siRNA screen and pursued as a tractable, novel target for cancer treatment. A screening campaign and systematic optimization, supported by computer modeling led to an indazole core with key sulfamoylphenyl and acetamido m... |
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