2’-脱氧肌苷三磷酸三钠盐
2’-脱氧肌苷三磷酸三钠盐结构式
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常用名 | 2’-脱氧肌苷三磷酸三钠盐 | 英文名 | 2'-DEOXYINOSINE-5'-TRIPHOSPHATE TRISODIUM SALT |
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| CAS号 | 95648-77-4 | 分子量 | 558.112 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C10H12N4Na3O13P3 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals.
Nucleic Acids Res. 38(9) , 2891-903, (2010) Mammalian inosine triphosphatase encoded by ITPA gene hydrolyzes ITP and dITP to monophosphates, avoiding their deleterious effects. Itpa(-) mice exhibited perinatal lethality, and significantly higher levels of inosine in cellular RNA and deoxyinosine in nuc... |
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Not as simple as ABC.
Microbiol. Sci. 5(5) , 152-3, (1988)
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Incorporation of dITP or 7-deaza dGTP during PCR improves sequencing of the product.
Nucleic Acids Res. 21(18) , 4427-8, (1993)
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Improved cycle sequencing of GC-rich templates by a combination of nucleotide analogs.
Biotechniques 29(2) , 268-70, (2000) A common problem in automated DNA sequencing when applying the Sanger chain termination method is ambiguous base calling caused by band compressions. Band compressions are caused by anomalies in the migration behavior of certain DNA fragments in the polyacryl... |
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Successful pyrosequencing of GC-rich DNA sequences by partial substitution of deoxyguanosine with deoxyinosine.
Diagn. Mol. Pathol. 19 , 123-125, (2010) We experienced significant problems while developing a PyrosequencingTM (Biotage, Uppsala, Sweden) assay to characterize the rifampin resistance-determining region of Mycobacteriumtuberculosis, a target with high guanosine-cytosine content. This paper describ... |
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ITPA protein, an enzyme that eliminates deaminated purine nucleoside triphosphates in cells. Sakumi K, Abolhassani N, et al.
Mutat. Res. 703 , 4-50, (2010)
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A comprehensive screening system for damaged nucleotide-binding proteins
Mutat. Res. 703 , 37-42, (2010) To identify novel nucleotide pool sanitizing enzymes, we have established a comprehensive screening system for damaged nucleotide-binding proteins based on proteomics technology. In the screening system, affinity chromatography with resins carrying various da... |
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Structure and activity of the Saccharomyces cerevisiae dUTP pyrophosphatase DUT1, an essential housekeeping enzyme.
Biochem. J. 437(2) , 243-53, (2011) Genomes of all free-living organisms encode the enzyme dUTPase (dUTP pyrophosphatase), which plays a key role in preventing uracil incorporation into DNA. In the present paper, we describe the biochemical and structural characterization of DUT1 (Saccharomyces... |
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Random mutagenesis by using mixtures of dNTP and dITP in PCR.
Methods Mol. Biol. 57 , 351-6, (1996)
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Gel compressions and artifact banding can be resolved in the same DNA sequence reaction.
Biotechniques 15(5) , 843-4, (1993)
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