美雄诺龙
美雄诺龙结构式
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常用名 | 美雄诺龙 | 英文名 | Mestanolone |
|---|---|---|---|---|
| CAS号 | 521-11-9 | 分子量 | 304.467 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 416.1±38.0 °C at 760 mmHg | |
| 分子式 | C20H32O2 | 熔点 | 191 °C | |
| MSDS | 中文版 美版 | 闪点 | 177.6±19.4 °C | |
| 符号 |
GHS08 |
信号词 | Warning |
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An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin.
J. Med. Chem. 51 , 2047-56, (2008) A benchmark data set of steroids with known affinity for sex hormone-binding globulin (SHBG) has been widely used to validate popular molecular field-based QSAR techniques. We have expanded the data set by adding a number of nonsteroidal SHBG ligands identifi... |
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Inhibitory effect and interaction of stanozolol with pig testicular cytochrome P-450 (17 alpha-hydroxylase/C17,20-lyase).
Chem. Pharm. Bull. 37(7) , 1855-8, (1989) The inhibitory effect of an anabolic steroid, stanozolol, on testicular microsomal cytochrome P-450 (17 alpha-hydroxylase/C17,20-lyase) (P-450(17 alpha/lyase] and the nature of the interaction were compared with those of other anabolic steroids, furazabol and... |
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Chemometric and chemoinformatic analyses of anabolic and androgenic activities of testosterone and dihydrotestosterone analogues.
Bioorg. Med. Chem. 16 , 6448-59, (2008) Predictive quantitative structure-activity relationship (QSAR) models of anabolic and androgenic activities for the testosterone and dihydrotestosterone steroid analogues were obtained by means of multiple linear regression using quantum and physicochemical m... |
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Testosterone content of developing eggs and sex reversal in the medaka (Oryzias latipes).
Gen. Comp. Endocrinol. 145(1) , 67-74, (2006) To understand the effect of testosterone on sex differentiation, the quantities of testosterone (T) and estradiol-17beta (E2) in developing eggs of medaka (Oryzias latipes) were measured by radioimmunoassay, and the influence on sex differentiation of treatin... |
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Identification and quantification of metabolites common to 17alpha-methyltestosterone and mestanolone in horse urine.
J. Pharm. Biomed. Anal. 45(1) , 125-33, (2007) Anabolic steroids with the 17alpha-methyl,17beta-hydroxyl group, which were developed as oral formulations for therapeutic purposes, have been abused in the field of human sports. These anabolic steroids are also used to enhance racing performance in racehors... |
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Assignment of anabolic-androgenic and antiandrogenic properties to some chlorine-substituted steroids on the basis of their binding characteristics to the androgen receptor of the rat seminal vesicle.
Exp. Clin. Endocrinol. 87(2) , 133-41, (1986) In this study we investigated the affinity of several 4-chlorinated and 1-ene derivatives of 17 alpha-methyltestosterone (MT) and 17 alpha-methyl-5 alpha-dihydrotestosterone (MDHT) to the androgen receptor, and, additionally, the effect of a few MT-derived st... |
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Ultrastructural changes induced by anabolic steroids in liver of trained rats.
Histol. Histopathol. 8(3) , 449-55, (1993) The effects of anabolic steroid treatment in association with endurance training on biochemical serum parameters and liver ultrastructure have been investigated in male rats. Values of serum alanine aminotransferase, aspartate aminotransferase and alkaline ph... |
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Effect of training and anabolic-androgenic steroids on drug metabolism in rat liver.
Med. Sci Sports Exerc. 25(7) , 815-22, (1993) The effects of anabolic-androgenic steroid administration and exercise training on various aspects of hepatic function were investigated in sedentary and trained (treadmill for 12 wk) male and female rats treated orally with fluoxymesterone or methylandrostan... |
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Gonadal differentiation and hormonal sex reversal in Arctic charr (Salvelinus alpinus).
J. Exp. Zool. A. Ecol. Genet. Physiol. 307(9) , 527-34, (2007) The purpose of this study was to develop a practical protocol for the production of female populations of Arctic charr (Salvelinus alpinus). Achieving this required knowledge of the timing of gonadal differentiation. Undifferentiated gonads were observed micr... |
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Synthesis and androgen receptor binding of dihydrotestosterone hemisuccinate homologs.
Steroids 55(6) , 259-62, (1990) Dihydrotestosterone-succinyl-agarose is the most common form of androgen affinity column. To investigate the effect of variation in the number of methylene groups between the ester and amide functions, a homologous series, varying the number of methylenes bet... |