氯甲酸(+)-1-(9-亚氟基)乙酯
氯甲酸(+)-1-(9-亚氟基)乙酯结构式
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常用名 | 氯甲酸(+)-1-(9-亚氟基)乙酯 | 英文名 | (+)-1-(9-fluorenyl)ethyl chloroformate |
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| CAS号 | 107474-79-3 | 分子量 | 272.72600 | |
| 密度 | 1.266g/cm3 | 沸点 | 398.8ºC at 760mmHg | |
| 分子式 | C16H13ClO2 | 熔点 | 94ºC | |
| MSDS | N/A | 闪点 | 145.7ºC | |
| 符号 |
GHS02, GHS05, GHS07 |
信号词 | Danger |
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Enantioselective analysis of D- and L-amino acids from mouse macrophages using high performance liquid chromatography.
J. Pharm. Biomed. Anal. 116 , 101-4, (2015) The intrinsic D-amino acid profile of mouse macrophages extracted from the peritoneal cavity was analyzed using high performance liquid chromatography. Six D-amino acids (D-Asp, D-Ser, D-Ala, D-Leu, D-Gln and D-Lys) were detected in cell lysates of mouse macr... |
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Separation and quantitation of the enantiomers of methamphetamine and its metabolites in urine by HPLC: precolumn derivatization and fluorescence detection.
J. Anal. Toxicol. 19(3) , 139-47, (1995) To study the disposition kinetics of methamphetamine (MAP), we have developed a sensitive high-performance liquid chromatographic (HPLC) assay to quantitate the enantiomers of MAP and its major metabolites, amphetamine (AP), p-hydroxymethamphetamine (p-OH-MAP... |
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Indirect resolution of beta-blocker agents by reversed-phase capillary electrochromatography.
Electrophoresis 25(4-5) , 607-14, (2004) The indirect resolution of five beta-adrenoreceptor blocking agents (propranolol, oxprenolol, pindolol, metoprolol, and atenolol) using precolumn derivatization with (+)-1-(9-fluorenyl)ethyl chloroformate (FLEC), and capillary electrochromatography (CEC) is r... |
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Recent progress in liquid chromatographic enantioseparation based upon diastereomer formation with fluorescent chiral derivatization reagents.
Biomed. Chromatogr. 10(6) , 265-77, (1996) Techniques for the resolution by liquid chromatography of racemic compounds based upon diastereomer formation with a fluorescent chiral reagent are outlined in this review. The tagging reagents for various functional groups, i.e. amine, carboxyl, hydroxyl and... |
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Chiral separation and detection enhancement of propranolol using automated pre-column derivatization.
J. Pharm. Biomed. Anal. 11(2) , 117-20, (1993) In the liquid chromatographic analysis of pharmaceuticals, two challenges are often encountered: detectivity and chiral separations. Propranolol, a beta adrenergic blocker, is a pharmaceutical compound that faces both of these limitations. In this study, both... |
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(+)-Fluorenylethylchloroformate (FLEC)--improved synthesis for application in chiral analysis and peptidomimetic synthesis.
Org. Biomol. Chem. 11(16) , 2571-3, (2013) An efficient synthesis of the enantiomers of fluorenylethylchloroformate (FLEC) has been achieved that allows the routine application of the reagent for the resolution of chiral amines including unusual amino acids. The utility of the fluorenylethoxycarbonyl ... |
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Separation of amino acid enantiomers and chiral amines using precolumn derivatization with (+)-1-(9-fluorenyl)ethyl chloroformate and reversed-phase liquid chromatography.
Anal. Chem. 59 , 1191, (1987)
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Enantioselective analysis of glufosinate using precolumn derivatization with (+)-1-(9-fluorenyl)ethyl chloroformate and reversed-phase liquid chromatography.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 2nd ed., 776 , 191, (2002) We have developed a new analytical method to quantify the DL-homoalanine-4-yl(methyl)phosphinate (DL-GLUF) enantiomers in biological specimens using a reversed-phase high-performance liquid chromatography system with a fluorescence detection system. The deriv... |
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Reversed-phase high-performance liquid chromatographic analysis of atenolol enantiomers in plasma after chiral derivatization with (+)-1-(9-fluorenyl)ethyl chloroformate.
J. Chromatogr. A. 568(1) , 239-45, (1991) A sensitive high-performance liquid chromatographic method for the determination of the enantiomers of atenolol in rat plasma has been developed. Racemic atenolol and practolol (internal standard) were extracted from alkalinized plasma (pH 12) into dichlorome... |
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High-performance liquid chromatographic determination of (SR)- and (RS)-enantiomers of mefloquine in plasma and capillary blood sampled on paper after derivatization with (-)-1-(9-fluorenyl)ethyl chloroformate.
J. Chromatogr. A. 652(1) , 73-81, (1994) A sensitive, stereoselective and rapid reversed-phase liquid chromatographic method for the determination of (SR)- and (RS)-mefloquine enantiomers in 100 microliters plasma and capillary blood collected on chromatographic paper is presented. The assay involve... |