5-溴-2-氟吡啶
5-溴-2-氟吡啶结构式
|
常用名 | 5-溴-2-氟吡啶 | 英文名 | 5-Brom-2-fluorpyridin |
|---|---|---|---|---|
| CAS号 | 766-11-0 | 分子量 | 175.99 | |
| 密度 | 1.7±0.1 g/cm3 | 沸点 | 178.0±20.0 °C at 760 mmHg | |
| 分子式 | C5H3BrFN | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 61.4±21.8 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Versatile synthesis of 3,5-disubstituted 2-fluoropyridines and 2-pyridones.
J. Org. Chem. 68(8) , 3352-5, (2003) 5-bromo-2-fluoro-3-pyridylboronic acid (3) was prepared in high yield by ortho-lithiation of 5-bromo-2-fluoropyridine (1), followed by reaction with trimethylborate. Suzuki reaction of 3 with a range of aryl iodides gave 3-monosubstituted 5-bromo-2-fluoropyri... |
|
|
Synthesis of two fluoro analogues of the nicotinic acetylcholine receptor agonist UB-165.
J. Org. Chem. 68(6) , 2475-8, (2003) Two racemic fluoropyridine analogues 4 and 5 of the potent nicotinic agonist UB-165 have been synthesized. Halogenated pyridines 7 and 12 provided the organometallic reagents needed for the Negishi and Suzuki coupling reactions used for the preparation of 4 a... |
|
|
Aromatic fluorine compounds. XI. Replacement of chlorine by fluorine in halopyridines. Finger GC, et al.
J. Org. Chem. 28(6) , 1666-1668, (1963)
|