吡咯戊酮
吡咯戊酮结构式
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常用名 | 吡咯戊酮 | 英文名 | Pyrovalerone hydrochloride solution |
|---|---|---|---|---|
| CAS号 | 1147-62-2 | 分子量 | 281.821 | |
| 密度 | N/A | 沸点 | 362.4ºC at 760mmHg | |
| 分子式 | C16H24ClNO | 熔点 | 171-174°C | |
| MSDS | 中文版 美版 | 闪点 | 127.3ºC | |
| 符号 |
GHS05, GHS07, GHS09 |
信号词 | Danger |
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[Issues on the use of ethnobotanicals].
Rev. Med. Chir. Soc. Med. Nat. Iasi. 115(4) , 1069-72, (2011) To identify the risk factors for the use of ethnobotanicals and the people at risk to becoming users.This questionnaire basez objective population study included 89 subjects aged 14 to 42 years.19.10% of the subjects admitted using ethnobotanicals, most of th... |
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1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors.
J. Med. Chem. 49(4) , 1420-32, (2006) Dopamine, serotonin, and norepinephrine are essential for neurotransmission in the mammalian system. These three neurotransmitters have been the focus of considerable research because the modulation of their production and their interaction at monoamine recep... |
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Toxicological determination and in vitro metabolism of the designer drug methylenedioxypyrovalerone (MDPV) by gas chromatography/mass spectrometry and liquid chromatography/quadrupole time-of-flight mass spectrometry.
Rapid Commun. Mass Spectrom. 24(18) , 2706-14, (2010) A method for the toxicological screening of the new designer drug methylenedioxypyrovalerone (MDPV) is described; with an emphasis on its application for anti-doping analysis. The metabolism of MDPV was evaluated in vitro using human liver microsomes and S9 c... |
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"Bath salts"-induced psychosis and serotonin toxicity.
J. Clin. Psychiatry 73(8) , 1125, (2012)
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Ivory wave: the next mephedrone?
Emerg. Med. J. 28(12) , 1059-60, (2011) Since the classification of miaow miaow (mephedrone) as a class B drug in April this year, a new drug is emerging as a so-called 'legal high'. Deaths have already been attributed to ivory wave in different parts of the country.A case study is presented, and r... |
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Identification of a pyrovalerone metabolite in the rat by gas chromatography-mass spectrometry and determination of pyrovalerone by gas chromatography-nitrogen-phosphorus detection.
J. Chromatogr. B, Biomed. Appl. 687(1) , 253-9, (1996) Pyrovalerone and its hydroxylated metabolite have been identified by gas chromatography-mass spectrometry in rat urine and plasma. A sensitive gas chromatographic method for the quantitative analysis of pyrovalerone in rat urine and plasma is described. The m... |
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Evidence that pure uptake inhibitors including cocaine interact slowly with the dopamine neuronal carrier.
Eur. J. Pharmacol. 264(3) , 391-8, (1994) We have studied the ability of various uptake blockers to protect the dopamine neuronal carrier labeled with [3H]GBR 12783 (1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-2-(propenyl)-piperazine) against N-ethylmaleimide-induced alkylation, using membrane preparati... |
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Detection and identification of pyrovalerone and its hydroxylated metabolite in the rat.
J. Anal. Toxicol. 20(7) , 568-72, (1996) Detection and identification of pyrovalerone and its metabolite, a hydroxylated product, are described. Their identities were confirmed by comparing their mass spectra and gas chromatographic retention times with those of the synthetic standards. The analytic... |
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A novel photoaffinity ligand for the dopamine transporter based on pyrovalerone.
Bioorg. Med. Chem. 17(11) , 3770-4, (2009) Non-tropane-based photoaffinity ligands for the dopamine transporter (DAT) are relatively unexplored in contrast to tropane-based compounds such as cocaine. In order to fill this knowledge gap, a ligand was synthesized in which the aromatic ring of pyrovalero... |
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The toxicology of bath salts: a review of synthetic cathinones.
J. Med. Toxicol. 8(1) , 33-42, (2012) Synthetic cathinones have recently emerged and grown to be popular drugs of abuse. Their dramatic increase has resulted in part from sensationalized media attention as well as widespread availability on the Internet. They are often considered "legal highs" an... |