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盐酸塞利洛尔

盐酸塞利洛尔结构式
盐酸塞利洛尔结构式
品牌特惠专场
常用名 盐酸塞利洛尔 英文名 Celiprolol HCl
CAS号 57470-78-7 分子量 415.955
密度 1.114g/cm3 沸点 586.5ºC at 760 mmHg
分子式 C20H34ClN3O4 熔点 197-200ºC (dec.)
MSDS N/A 闪点 308.5ºC

Highly sensitive transient isotachophoresis sample stacking coupling with capillary electrophoresis-amperometric detection for analysis of doping substances

Talanta 81(4-5) , 1288-94, (2010)

A simple and effective method of capillary electrophoresis-amperometric detection (CE–AD) coupled with transient isotachophoresis (tITP) was developed for the trace determination of doping substances. Compared with the conventional capillary electrophoresis m...

Simultaneous separation of eight beta-adrenergic drugs using titanium dioxide nanoparticles as additive in capillary electrophoresis.

Electrophoresis 29(11) , 2321-9, (2008)

The analysis is described for separating seven beta-adrenergic blocking agents (atenolol, celiprolol, clorprenaline, fenoterol, metoprolol, propranolol, terbutaline) and clenbuterol (sympathomimetic beta-2 receptor stimulating agonist, decongestant and bronch...

Direct determination of celiprolol in human urine using on-line coupled ITP-CZE method with fiber-based DAD.

Electrophoresis 29(22) , 4561-7, (2008)

The present work illustrated possibilities of column-coupling electrophoresis combined with DAD for the direct quantitative determination of trace drug (celiprolol, CEL) in clinical human urine samples. ITP, on-line coupled with CZE, served as an ideal inject...

Celiprolol, a selective beta1-blocker, reduces the infarct size through production of nitric oxide in a rabbit model of myocardial infarction.

Circ. J. 71(4) , 574-9, (2007)

It is still unclear whether celiprolol, a beta(1)-selective blocker, reduces myocardial infarct size. This study will examine whether celiprolol reduces myocardial infarct size, as well as investigate the mechanisms for its infarct size-reducing effect in rab...

Effects of itraconazole, dexamethasone and naringin on the pharmacokinetics of nadolol in rats.

Drug Metab. Pharmacokinet. 28(4) , 356-61, (2013)

The aim of the present study was to clarify the involvement of P-glycoprotein (P-gp) or organic anion transporting polypeptide (Oatp) 1a5 in the pharmacokinetics of nadolol (NDL), a non-metabolized hydrophilic β-adrenoceptor blocker, in rats. Pretreatment wit...

Hesperidin in orange juice reduces the absorption of celiprolol in rats.

Biopharm. Drug Dispos. 29(3) , 185-8, (2008)

It has been reported that the intestinal absorption of celiprolol, an antihypertensive drug, is inhibited when it is taken with orange juice; it has been suggested that element(s) in citrus juice are responsible for this. In the present study, the pharmacokin...

Fluorometric determination of bopindolol and celiprolol in pharmaceutical preparations and biological fluids.

J. Fluoresc. 22(4) , 1141-50, (2012)

Two sensitive fluorometric methods were developed for the determination of both bopindolol malonate (BOP) and celiprolol HCl (CLP) based on measuring their native fluorescence in methanol and acetonitrile, respectively. For BOP, the fluorescence was measured ...

A vasodilating β1 blocker celiprolol inhibits muscular release of uric acid precursor in patients with essential hypertension.

Horm. Metab. Res. 45(1) , 69-73, (2013)

Although nonvasodilating β1 blockers increase the levels of uric acid in serum, it is not known whether vasodilating β1 blockers have a similar effect. In the present study, we evaluated the effect of celiprolol on the release of hypoxanthine, a uric acid pre...

[Vascular Ehlers-Danlos syndrome and pregnancy: an obstetrical specific support].

J. Gynecol. Obstet. Biol. Reprod. (Paris.) 41(7) , 676-8, (2012)

The Ehlers-Danlos syndrome (EDS) is a rare inheritable disease, characterised by a defect in collagen synthesis. Various types have been described and the type IV or vascular type is the most severe characterised by vascular, gastrointestinal and gynaecologic...

Celiprolol-induced lupus-like syndrome.

Acta Cardiol. 61(6) , 661-3, (2006)

Systemic lupus erythematosus can be idiopathic or drug-induced. Although a number of beta-blockers have been reported to induce a lupus-like syndrome, to the best of our knowledge, no such case has been described following celiprolol therapy. We diagnosed a l...