斑鸠霉素
斑鸠霉素结构式
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常用名 | 斑鸠霉素 | 英文名 | Ikarugamycin |
|---|---|---|---|---|
| CAS号 | 36531-78-9 | 分子量 | 478.62 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 741.9±60.0 °C at 760 mmHg | |
| 分子式 | C29H38N2O4 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 402.5±32.9 °C | |
| 符号 |
GHS06 |
信号词 | Danger |
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Pathogen- and Host-Directed Antileishmanial Effects Mediated by Polyhexanide (PHMB).
PLoS Negl. Trop. Dis. 9 , e0004041, (2015) Cutaneous leishmaniasis (CL) is a neglected tropical disease caused by protozoan parasites of the genus Leishmania. CL causes enormous suffering in many countries worldwide. There is no licensed vaccine against CL, and the chemotherapy options show limited ef... |
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Clathrin-dependent and independent endocytic pathways in tobacco protoplasts revealed by labelling with charged nanogold.
J. Exp. Bot. 59(11) , 3051-68, (2008) Positively charged nanogold was used as a probe to trace the internalization of plasma membrane (PM) domains carrying negatively charged residues at an ultrastructural level. The probe revealed distinct endocytic pathways within tobacco protoplasts and allowe... |
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Distinct endocytic pathways identified in tobacco pollen tubes using charged nanogold.
J. Cell Sci. 120(Pt 21) , 3804-19, (2007) In an attempt to dissect endocytosis in Nicotiana tabacum L. pollen tubes, two different probes--positively or negatively charged nanogold--were employed. The destiny of internalized plasma membrane domains, carrying negatively or positively charged residues,... |
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Clathrin-independent endocytosis contributes to uptake of glucose into BY-2 protoplasts.
Plant J. 70(4) , 578-84, (2012) In eukaryotic cells, several pathways exist for the internalization of plasma membrane proteins and extracellular cargo molecules. These endocytic pathways can be divided into clathrin-dependent and clathrin-independent pathways. While clathrin-dependent path... |
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Inhibition of the uptake of oxidized low-density lipoprotein in macrophage J774 by the antibiotic ikarugamycin.
Eur. J. Biochem. 205(2) , 841-6, (1992) The antiprotozoal antibiotic ikarugamycin was found to significantly inhibit oxidized low-density lipoprotein(LDL)-induced accumulation of cholesteryl ester in macrophage J774 at a concentration over 1-4 microM. Cholesteryl ester synthesis from [14C]oleate in... |
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Human immunodeficiency virus type 1 Nef-induced CD4 cell surface downregulation is inhibited by ikarugamycin.
J. Virol. 75(5) , 2488-92, (2001) One well-characterized in vitro function of Nef is its ability to remove CD4, the human immunodeficiency virus (HIV) receptor, from the cell surface. Nef accomplishes this by accelerating the internalization and degradation of CD4. Current models propose that... |
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Streptomyces harbinensis sp. nov., an endophytic, ikarugamycin-producing actinomycete isolated from soybean root [Glycine max (L.) Merr].
Int. J. Syst. Evol. Microbiol. 63(Pt 10) , 3579-84, (2013) A novel ikarugamycin-producing actinomycete, designated strain NEAU-Da3(T), was isolated from soybean root [Glycine max (L.) Merr.] and characterized using a polyphasic approach. 16S rRNA gene sequence similarity studies showed that strain NEAU-Da3(T) belonge... |