CP-135807
CP-135807结构式
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常用名 | CP-135807 | 英文名 | CP-135807 |
|---|---|---|---|---|
| CAS号 | 151272-90-1 | 分子量 | 351.40200 | |
| 密度 | 1.343g/cm3 | 沸点 | 548.7ºC at 760 mmHg | |
| 分子式 | C19H21N5O2 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 285.6ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Combined administration of a 5-hydroxytryptamine (5-HT)1D antagonist and a 5-HT reuptake inhibitor synergistically increases 5-HT release in guinea pig hypothalamus in vivo.
J. Neurochem. 67(5) , 2204-7, (1996) In vivo microdialysis in guinea pig hypothalamus was used to study the effect of serotonin [5-hydroxytryptamine (5-HT)] subtype 1D autoreceptor blockade on the increase in extracellular 5-HT levels produced by a selective 5-HT reuptake inhibitor (SSRI). Admin... |
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In vitro characterization of AR-A000002, a novel 5-hydroxytryptamine(1B) autoreceptor antagonist.
Eur. J. Pharmacol. 499(1-2) , 67-75, (2004) The in vitro pharmacological properties of AR-A000002 ((R)-N-[5-methyl-8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-2-naphthyl]-4-morpholinobenzamide), a novel 5-hydroxytryptamine (5-HT)(1B) receptor antagonist, were studied. AR-A000002 bound with high affin... |
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