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(R)-(+)-1-氨基-2-(甲氧基甲基)吡咯烷

(R)-(+)-1-氨基-2-(甲氧基甲基)吡咯烷结构式
(R)-(+)-1-氨基-2-(甲氧基甲基)吡咯烷结构式
品牌特惠专场
常用名 (R)-(+)-1-氨基-2-(甲氧基甲基)吡咯烷 英文名 (r)-(+)-1-amino-2-(methoxymethyl)pyrrolidine
CAS号 72748-99-3 分子量 130.188
密度 1.0±0.1 g/cm3 沸点 183.7±13.0 °C at 760 mmHg
分子式 C6H14N2O 熔点 N/A
MSDS 中文版 美版 闪点 64.9±19.8 °C

SCF ubiquitin ligase-targeted therapies.

Nat. Rev. Drug Discov. 13(12) , 889-903, (2014)

The clinical successes of proteasome inhibitors for the treatment of cancer have highlighted the therapeutic potential of targeting this protein degradation system. However, proteasome inhibitors prevent the degradation of numerous proteins, which may cause a...

Endogenous VMH amylin signaling is required for full leptin signaling and protection from diet-induced obesity.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 310 , R355-65, (2016)

Amylin enhances arcuate (ARC) and ventromedial (VMN) hypothalamic nuclei leptin signaling and synergistically reduces food intake and body weight in selectively bred diet-induced obese (DIO) rats. Since DIO (125)I-amylin dorsomedial nucleus-dorsomedial VMN bi...