![]() (r)-(+)-1-amino-2-(methoxymethyl)pyrrolidine structure
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Common Name | (r)-(+)-1-amino-2-(methoxymethyl)pyrrolidine | ||
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CAS Number | 72748-99-3 | Molecular Weight | 130.188 | |
Density | 1.0±0.1 g/cm3 | Boiling Point | 183.7±13.0 °C at 760 mmHg | |
Molecular Formula | C6H14N2O | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 64.9±19.8 °C |
SCF ubiquitin ligase-targeted therapies.
Nat. Rev. Drug Discov. 13(12) , 889-903, (2014) The clinical successes of proteasome inhibitors for the treatment of cancer have highlighted the therapeutic potential of targeting this protein degradation system. However, proteasome inhibitors prevent the degradation of numerous proteins, which may cause a... |
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Endogenous VMH amylin signaling is required for full leptin signaling and protection from diet-induced obesity.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 310 , R355-65, (2016) Amylin enhances arcuate (ARC) and ventromedial (VMN) hypothalamic nuclei leptin signaling and synergistically reduces food intake and body weight in selectively bred diet-induced obese (DIO) rats. Since DIO (125)I-amylin dorsomedial nucleus-dorsomedial VMN bi... |
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