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1-茚醇

1-茚醇结构式
1-茚醇结构式
品牌特惠专场
常用名 1-茚醇 英文名 2,3-Dihydro-1H-inden-1-ol
CAS号 6351-10-6 分子量 134.175
密度 1.2±0.1 g/cm3 沸点 255.1±9.0 °C at 760 mmHg
分子式 C9H10O 熔点 50-53 °C
MSDS 中文版 美版 闪点 89.2±11.0 °C
符号 GHS07
GHS07
信号词 Warning

Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.

J. Pharmacol. Exp. Ther. 335 , 533-545, (2010)

Doxorubicin (DOX) and daunorubicin (DAUN) are effective anticancer drugs; however, considerable interpatient variability exists in their pharmacokinetics. This may be caused by altered metabolism by nonsynonymous single-nucleotide polymorphisms (ns-SNPs) in g...

Determination of the single component and competitive adsorption isotherms of the 1-indanol enantiomers by the inverse method.

J. Chromatogr. A. 1005(1-2) , 35-49, (2003)

The inverse method of isotherm determination consists in calculating the numerical values of the coefficients of an isotherm model that give a set of chromatographic profiles in best possible agreement with the set of experimental profiles available. This met...

Conformational landscapes and free-jet rotational spectrum of indan-1-ol.

ChemPhysChem 7(3) , 565-8, (2006)

Desaturation, dioxygenation, and monooxygenation reactions catalyzed by naphthalene dioxygenase from Pseudomonas sp. strain 9816-4.

J. Bacteriol. 177(10) , 2615-21, (1995)

The stereospecific oxidation of indan and indene was examined with mutant and recombinant strains expressing naphthalene dioxygenase of Pseudomonas sp. strain 9816-4. Pseudomonas sp. strain 9816/11 and Escherichia coli JM109(DE3)[pDTG141] oxidized indan to (+...

Heterogeneous adsorption of 1-indanol on cellulose tribenzoate and adsorption energy distribution of the two enantiomers.

Anal. Chem. 76(1) , 197-202, (2004)

The distributions of the adsorption energies (AED) of two enantiomers, (R)-1- indanol and (S)-1-indanol, on a chiral stationary phase were measured and the results are discussed. The chiral phase used is made of cellulose tribenzoate coated on porous silica. ...

Stereospecific oxidation of (R)- and (S)-1-indanol by naphthalene dioxygenase from Pseudomonas sp. strain NCIB 9816-4.

Appl. Environ. Microbiol. 63(5) , 2067-70, (1997)

A recombinant Escherichia coli strain which expresses naphthalene dioxygenase (NDO) from Pseudomonas sp. strain NCIB 9816-4 oxidized (S)-1-indanol to trans-(1S,3S)-indan-1,3-diol (95.5%) and (R)-3-hydroxy-1-indanone (4.5%). The same cells oxidized (R)-1-indan...

Development of a bioconversion process for production of cis-1S,2R-indandiol from indene by recombinant Escherichia coli constructs.

Appl. Microbiol. Biotechnol. 51(5) , 614-20, (1999)

Recombinant Escherichia coli cells expressing the toluene dioxygenase (TDO) genes from Pseudomonas putida convert indene to cis-1S,2R-indandiol, a potentially important intermediate for the chemical synthesis of the HIV-1 protease inhibitor, Crixivan. A bioco...

Comparison of the binary equilibrium isotherms of the 1-indanol enantiomers on three high-performance liquid chromatography columns of different sizes.

J. Chromatogr. A. 1015(1-2) , 73-87, (2003)

The competitive isotherm data for the enantiomers of 1-indanol were measured on three columns, a microbore column (15 cm x 0.1 cm), a conventional analytical column (15 cm x 0.46 cm), and a semi-preparative column (20 cm x 1.0 cm), packed with Chiralcel OB. T...

Kinetic studies of the inhibition of a human liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase isozyme by bile acids and anti-inflammatory drugs.

Biol. Pharm. Bull. 18(1) , 9-12, (1995)

We have investigated the steady-state kinetics for a cytosolic 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase isozyme of human liver and its inhibition by several bile acids and anti-inflammatory drugs such as indomethacin, flufemanic acid and naproxen. Ini...

Chirality-dependent balance between hydrogen bonding and London dispersion in isolated (±)-1-indanol clusters.

Phys. Chem. Chem. Phys. 15(25) , 10167-80, (2013)

The aggregation behavior of racemic and enantiopure 1-indanol has been studied by FTIR spectroscopy, resonant ion dip IR spectroscopy, and spontaneous Raman scattering in supersonic jets. This triple experimental approach, augmented by homology to related mol...