碘番酸
碘番酸结构式
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常用名 | 碘番酸 | 英文名 | Iopanoic acid |
|---|---|---|---|---|
| CAS号 | 96-83-3 | 分子量 | 570.93200 | |
| 密度 | 2.426g/cm3 | 沸点 | 529.1ºC at 760mmHg | |
| 分子式 | C11H12I3NO2 | 熔点 | 153 °C | |
| MSDS | 中文版 美版 | 闪点 | 273.8ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Regulation and function of deiodinases during decidualization in female mice.
Endocrinology 155(7) , 2704-17, (2014) Thyroid dysfunction during human pregnancy is closely related to serious pregnancy outcome. However, the regulation and function of thyroid hormones during early pregnancy are largely unknown. We found that type II deiodinase, an enzyme converting T4 to activ... |
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Crystallographic analysis reveals the structural basis of the high-affinity binding of iophenoxic acid to human serum albumin.
BMC Struct. Biol. 11 , 18, (2011) Iophenoxic acid is an iodinated radiocontrast agent that was withdrawn from clinical use because of its exceptionally long half-life in the body, which was due in part to its high-affinity binding to human serum albumin (HSA). It was replaced by Iopanoic acid... |
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Liquid chromatography-electrospray ionization mass spectrometry for direct identification and quantification of iophenoxic acid in serum.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 832(1) , 144-57, (2006) A liquid chromatographic-electrospray ionization mass spectrometric technique was developed for direct quantitation of iophenoxic acid (IA) in serum. IA was spiked into canine, feline, bovine, equine, and porcine sera, extracted, and quantified using negative... |
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Analysis by LC/ESI-MS of iophenoxic acid derivatives and evaluation as markers of oral baits to deliver pharmaceuticals to wildlife.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 878(22) , 1997-2002, (2010) Iophenoxic acid and its derivatives (methyl, ethyl, and propyl) are organic chemicals used as markers in baiting campaigns to deliver vaccines, pharmaceuticals, contraceptives or poisons to wildlife. In this study we develop a method of detection of IPA deriv... |
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Iophenoxic acid derivatives as markers of oral baits to wildlife. New tools for their detection in tissues of a game species and safety considerations for human exposure.
Environ. Sci. Pollut. Res. Int. 20(5) , 2893-904, (2013) The bait-marker iophenoxic acid (IPA) and its derivatives are increasingly used for evaluating and optimizing the cost-effectiveness of baiting campaigns on wildlife, particularly on game species such as the wild boar. We aimed to determine whether concentrat... |
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Long-lasting systemic bait markers for Eurasian badgers.
J. Wildl. Dis. 42(4) , 892-6, (2006) This study was carried out to assess whether Rhodamine B, ethyl-iophenoxic acid (EtIPA), and propyl-iophenoxic acid (PrIPA) can be used as long-lasting systemic bait markers for free-living badgers (Meles meles). Between June and November 2003, these chemical... |
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Vaccination of feral pigs (Sus scrofa) using iophenoxic acid as a simulated vaccine.
Aust. Vet. J. 86(1-2) , 50-5, (2008) To develop an encapsulation method for delivery of vaccines to feral pigs, and quantify the effect of iophenoxic acid on captive feral pig blood iodine concentrations to assist in investigation of factors affecting vaccine uptake.Feral pigs were administered ... |
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Binding of diuretic antihypertensive bendroflumethiazide to human serum albumin studied by ¹⁹F nuclear magnetic resonance method.
Eur. J. Pharm. Sci. 45(1-2) , 195-200, (2012) Simultaneous specific and nonspecific binding of bendroflumethiazide (BFZ) to human serum albumin (HSA) and concentration profile of BFZ in HSA buffer (pH 7.40) solution were investigated by ¹⁹F nuclear magnetic resonance (NMR) method. The ¹⁹F NMR spectrum of... |
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Amiodarone-induced thyrotoxicosis. A review.
Minerva Endocrinol. 33(3) , 213-28, (2008) Amiodarone (AM), a potent class III anti-arrhythmic drug, is an iodine-rich compound with a structural resemblance to thyroid hormones triiodothyronine (T3) and thyroxine (T4). At the commonly employed doses, AM causes iodine overload up to 50-100 times the o... |
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The thyroid hormone degrading type 3 deiodinase is the primary deiodinase active in murine epidermis.
Thyroid 21(11) , 1263-8, (2011) Many tissues express thyroid hormone metabolizing deiodinases that both activate and inactivate thyroid hormones through conversion processes. Many believe that the primary role of thyroid hormone deiodinases is the activation of the prohormone thyroxine (T(4... |