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溴酚蓝

溴酚蓝结构式
溴酚蓝结构式
品牌特惠专场
常用名 溴酚蓝 英文名 Bromophenol Blue
CAS号 115-39-9 分子量 669.961
密度 2.2±0.1 g/cm3 沸点 605.6±55.0 °C at 760 mmHg
分子式 C19H10Br4O5S 熔点 273 °C
MSDS 中文版 美版 闪点 320.1±31.5 °C
符号 GHS02 GHS07 GHS08
GHS02, GHS07, GHS08
信号词 Danger

Genetic and pharmacologic inhibition of eIF4E reduces breast cancer cell migration, invasion, and metastasis.

Cancer Res. 75(6) , 1102-12, (2015)

The translation initiation factor eIF4E is an oncogene that is commonly overexpressed in primary breast cancers and metastases. In this article, we report that a pharmacologic inhibitor of eIF4E function, ribavirin, safely and potently suppresses breast tumor...

Proteasome-mediated degradation of FRIGIDA modulates flowering time in Arabidopsis during vernalization.

Plant Cell 26(12) , 4763-81, (2015)

Winter-annual accessions of Arabidopsis thaliana require either exposure to cold stress or vernalization to initiate flowering via FRIGIDA (FRI). FRI acts as a scaffold protein to recruit several chromatin modifiers that epigenetically modify flowering genes....

Insulin-like growth factor 1 increases apical fibronectin in blastocysts to increase blastocyst attachment to endometrial epithelial cells in vitro.

Hum. Reprod. 30(2) , 284-98, (2015)

Does insulin-like growth factor 1 (IGF1) increase adhesion competency of blastocysts to increase attachment to uterine epithelial cells in vitro?IGF1 increases apical fibronectin on blastocysts to increase attachment and invasion in an in vitro model of impla...

P2X1-initiated p38 signalling enhances thromboxane A2-induced platelet secretion and aggregation.

Thromb. Haemost. 112(1) , 142-50, (2014)

ATP released by activated platelets can serve as a positive feedback machinery to amplify platelet responses by activating P2X1 receptors. It has, however, not been defined how P2X1 activities influence thromboxane A2 (TXA2)-stimulated platelet functional res...

Blocking of the interaction between Wnt proteins and their co-receptors contributes to the anti-tumor effects of adenovirus-mediated DKK3 in glioblastoma.

Cancer Lett. 356(2 Pt B) , 496-505, (2014)

The effect of the third member of the Dickkopf family (DKK3) in the Wnt pathway in glioblastoma remains unclear. We first demonstrated the non-specific interaction of Wnt3a and Wnt5a with the receptors LRP6 and ROR2 and the up-regulation of the Wnt pathway in...

H89 enhances the sensitivity of cancer cells to glyceryl trinitrate through a purinergic receptor-dependent pathway.

Oncotarget 6(9) , 6877-86, (2015)

High doses of the organic nitrate glyceryl trinitrate (GTN), a nitric oxide (NO) donor, are known to trigger apoptosis in human cancer cells. Here, we show that such a cytotoxic effect can be obtained with subtoxic concentrations of GTN when combined with H89...

Kafirin adsorption on ion-exchange resins: isotherm and kinetic studies.

J. Chromatogr. A. 1356 , 105-16, (2014)

Kafirin is a natural, hydrophobic and celiac safe prolamin protein obtained from sorghum seeds. Today kafirin is found to be useful in designing delayed delivery systems and coatings of pharmaceuticals and nutraceuticals where its purity is important and this...

Disturbed Hsp70 and Hsp27 expression and thiol redox status in porcine kidney PK15 cells provoked by individual and combined ochratoxin A and citrinin treatments.

Food Chem. Toxicol. 71 , 97-105, (2014)

The aim of this study was to explore the oxidative properties of ochratoxin A (OTA) and citrinin (CTN) as a possible underlying mechanism of their individual and/or combined cytotoxicity. Metabolic activity of PK15 porcine kidney cells was significantly reduc...

Mutations in MAB21L2 result in ocular Coloboma, microcornea and cataracts.

PLoS Genet. 11(2) , e1005002, (2015)

Ocular coloboma results from abnormal embryonic development and is often associated with additional ocular and systemic features. Coloboma is a highly heterogeneous disorder with many cases remaining unexplained. Whole exome sequencing from two cousins affect...

EGFR signaling downstream of EGF regulates migration, invasion, and MMP secretion of immortalized cells derived from human ameloblastoma.

Tumour Biol. 35(11) , 11107-20, (2014)

Ameloblastoma is an odontogenic tumor characterized by local invasiveness and frequent recurrence. The surrounding stroma, composed of different cell types and extracellular matrix (ECM), may influence ameloblastoma invasive behavior. Furthermore, tumor and s...