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N-羟基哌啶

N-羟基哌啶结构式
N-羟基哌啶结构式
品牌特惠专场
常用名 N-羟基哌啶 英文名 N-Hydroxypiperidine
CAS号 4801-58-5 分子量 101.14700
密度 1.07g/cm3 沸点 175.7ºC at 760 mmHg
分子式 C5H11NO 熔点 37-39ºC
MSDS 中文版 美版 闪点 78ºC

Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages.

PLoS ONE 7(12) , e52790, (2012)

Latent M. tuberculosis infection presents one of the major obstacles in the global eradication of tuberculosis (TB). Cholesterol plays a critical role in the persistence of M. tuberculosis within the macrophage during latent infection. Catabolism of cholester...

Biological N-oxidation of piperidine in vitro.

Zhongguo Yao Li Xue Bao 10(3) , 252-6, (1989)

The biological N-oxidation of piperidine, a pharmacologically active biogenic amine of mammals and human beings, was studied in vitro. After incubation of piperidine-HCl in a fortified rat liver microsomal preparation (9000 x g supernatant) at 37 degrees C fo...

On the effect of thalidomide on Mycobacterium avium subspecies paratuberculosis in culture.

Int. J. Infect. Dis. 13(5) , e254-63, (2009)

Without known mechanisms of action, thalidomide is used to treat a variety of non-malignant 'idiopathic' diseases. There is increasing concern that Mycobacterium avium subspecies paratuberculosis (MAP) may be zoonotic. Recently, methotrexate, azathioprine, 6-...