N-Hydroxypiperidine
N-Hydroxypiperidine structure
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Common Name | N-Hydroxypiperidine | ||
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| CAS Number | 4801-58-5 | Molecular Weight | 101.14700 | |
| Density | 1.07g/cm3 | Boiling Point | 175.7ºC at 760 mmHg | |
| Molecular Formula | C5H11NO | Melting Point | 37-39ºC | |
| MSDS | Chinese USA | Flash Point | 78ºC | |
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Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages.
PLoS ONE 7(12) , e52790, (2012) Latent M. tuberculosis infection presents one of the major obstacles in the global eradication of tuberculosis (TB). Cholesterol plays a critical role in the persistence of M. tuberculosis within the macrophage during latent infection. Catabolism of cholester... |
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Biological N-oxidation of piperidine in vitro.
Zhongguo Yao Li Xue Bao 10(3) , 252-6, (1989) The biological N-oxidation of piperidine, a pharmacologically active biogenic amine of mammals and human beings, was studied in vitro. After incubation of piperidine-HCl in a fortified rat liver microsomal preparation (9000 x g supernatant) at 37 degrees C fo... |
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On the effect of thalidomide on Mycobacterium avium subspecies paratuberculosis in culture.
Int. J. Infect. Dis. 13(5) , e254-63, (2009) Without known mechanisms of action, thalidomide is used to treat a variety of non-malignant 'idiopathic' diseases. There is increasing concern that Mycobacterium avium subspecies paratuberculosis (MAP) may be zoonotic. Recently, methotrexate, azathioprine, 6-... |