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乙氧基乙酸

乙氧基乙酸结构式
乙氧基乙酸结构式
品牌特惠专场
常用名 乙氧基乙酸 英文名 Ethoxyacetic acid
CAS号 627-03-2 分子量 104.10500
密度 1.102 g/mL at 25 °C(lit.) 沸点 97-100 °C11 mm Hg(lit.)
分子式 C4H8O3 熔点 N/A
MSDS 中文版 美版 闪点 208 °F
符号 GHS05
GHS05
信号词 Danger

Decrease of intracellular pH as possible mechanism of embryotoxicity of glycol ether alkoxyacetic acid metabolites.

Toxicol. Appl. Pharmacol. 245(2) , 236-43, (2010)

Embryotoxicity of glycol ethers is caused by their alkoxyacetic acid metabolites, but the mechanism underlying the embryotoxicity of these acid metabolites is so far not known. The present study investigates a possible mechanism underlying the embryotoxicity ...

Chemical class-specific gene expression changes in the zebrafish embryo after exposure to glycol ether alkoxy acids and 1,2,4-triazole antifungals.

Reprod. Toxicol. 32(2) , 245-52, (2011)

The zebrafish embryotoxicity test (ZET) is an alternative test to predict embryotoxicity of substances based on morphological assessment. Implementing transcriptomics may increase sensitivity and objectivity of the test system. We applied the category approac...

Mutagenicity of ethylene glycol ethers and of their metabolites in Salmonella typhimurium his-.

Mutat. Res. 341(4) , 281-7, (1995)

Ethylene glycol ethers, their aldehyde and their acid metabolites were evaluated for their mutagenicity with the Ames test. The Salmonella typhimurium his- tester strains TA 97a, TA 98, TA 100 and TA 102 were used with and without rat S9 mix. Ethylene glycol ...

Rat model for renal effects of 2-alkoxyalcohols and their acetates.

Arch. Toxicol. 73(4-5) , 229-32, (1999)

Male Wistar rats were given ethanediol (9.4 g/l), 2-ethoxyethylacetate (5.4 g/l), 2-butoxyethylacetate (2.9 g/l) and 1,2-propanediol (40 g/l) respectively in their drinking water for 2 weeks. Urine was collected during the last 24 h of the exposure. There was...

Improved method to measure urinary alkoxyacetic acids.

Occup. Environ. Med. 56(7) , 460-7, (1999)

To simplify the current preparation of samples, and to improve the specificity and reliability of the conventional analytical methods to measure urinary alkoxyacetic acids.Samples containing alkoxyacetic acids including methoxy, ethoxy, and butoxyacetic acids...

Determination of urinary alkoxyacetic acids by a rapid and simple method for biological monitoring of workers exposed to glycol ethers and their acetates.

Int. Arch. Occup. Environ. Health 64(7) , 495-8, (1993)

In control subjects and workers exposed to glycol ethers and their acetates, we determined the urinary metabolites (three alkoxyacetic acids) by a simple and rapid method. Levels of urinary metabolites were significantly higher in the solvent workers than in ...

The biological exposure index: its use in assessing chemical exposures in the workplace.

Toxicology 47(1-2) , 55-69, (1987)

Human exposure to chemicals in the workplace has traditionally been assessed by determining the concentration of an airborne chemical in the workroom air. More recently, biological monitoring has been used to assess worker uptake of chemicals by all routes of...

Health effects of exposure to ethylene glycol monoethyl ether in female workers.

Ind. Health 42(4) , 447-51, (2004)

Ethylene glycol monoethyl ether (EGEE) is a solvent commonly used in industry. To find the health effect of the solvent exposure in women, we did an investigation on 32 female workers exposed to EGEE in factories manufacturing photopolymer sensitization plate...

Decreased formation of ethoxyacetic acid from ethylene glycol monoethyl ether and reduced atrophy of testes in male rats upon combined administration with toluene and xylene.

Toxicol. Lett. 104(1-2) , 143-50, (1999)

Male painters are commonly exposed to ethylene glycol monoethyl ether (EGE), a well known reproductive toxic agent causing testicular atrophy, in the form of solvent mixture containing toluene (TOL) and xylene (XYL). This study was carried out to determine th...

Applications of biological monitoring in occupational health practice: practical application of urinary 2-ethoxyacetic acid to assess exposure to 2-ethoxyethyl acetate in large format silk-screening operations.

Int. Arch. Occup. Environ. Health 65(1 Suppl) , S47-51, (1993)

A practical application of urinary 2-ethoxyacetic acid (EAA) to assess occupational exposure to 2-ethoxyethyl acetate (EGEE-Ac) during a large format silk-screening operation is described. Industrial hygiene air monitoring of employees of a silk-screen shop p...