芒果苷
芒果苷结构式
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常用名 | 芒果苷 | 英文名 | Mangiferin |
|---|---|---|---|---|
| CAS号 | 4773-96-0 | 分子量 | 422.340 | |
| 密度 | 1.8±0.1 g/cm3 | 沸点 | 842.7±65.0 °C at 760 mmHg | |
| 分子式 | C19H18O11 | 熔点 | 269-270ºC | |
| MSDS | 中文版 美版 | 闪点 | 303.6±27.8 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Thermal Degradation Kinetics Modeling of Benzophenones and Xanthones during High-Temperature Oxidation of Cyclopia genistoides (L.) Vent. Plant Material.
J. Agric. Food Chem. 63 , 5518-27, (2015) Degradation of the major benzophenones, iriflophenone-3-C-glucoside-4-O-glucoside and iriflophenone-3-C-glucoside, and the major xanthones, mangiferin and isomangiferin, of Cyclopia genistoides followed first-order reaction kinetics during high-temperature ox... |
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[Chemical constituents of Gentiana rhodantha].
Zhongguo Zhong Yao Za Zhi 38(3) , 362-5, (2013) To determine the chemical constituents of Gentiana rhodantha.To isolate the constituents, column chromatography over silica gel, MCI, Sephadex LH-20 and C18 reverse-phased silica gel were used. Spectroscopic methods were used to elucidate the structures of th... |
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Mangiferin activates the Nrf2-ARE pathway and reduces etoposide-induced DNA damage in human umbilical cord mononuclear blood cells.
Pharm. Biol. 53(4) , 503-11, (2015) Mangiferin (2-C-β-d-gluco-pyranosyl-1,3,6,7-tetrahydroxyxanthone) is a well-known natural antioxidant distributed in various plants of the Anacardiaceae and Gentianaceae families. Mangiferin can inhibit carcinogen-induced lung or colon tumor formation in expe... |
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Divide and Conquer May Not Be the Optimal Approach to Retain the Desirable Estrogenic Attributes of the Cyclopia Nutraceutical Extract, SM6Met.
PLoS ONE 10 , e0132950, (2015) The genus Cyclopia, an indigenous South African fynbos plant used to prepare honeybush tea, contains phytoestrogenic compounds. An extract from C. subternata, SM6Met, displays three desirable estrogenic attributes for future development of a phytoestrogenic n... |
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Mangiferin attenuates renal ischemia-reperfusion injury by inhibiting inflammation and inducing adenosine production.
Int. Immunopharmacol. 25(1) , 148-54, (2015) Ischemia reperfusion injury (IRI) is a leading cause of acute kidney injury, which is associated with high morbidity. The aims of the present study were to examine whether mangiferin attenuates renal IRI in an animal model and to identify the underlying mecha... |
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Estrogen modulation properties of mangiferin and quercetin and the mangiferin metabolite norathyriol.
Food Funct. 6 , 1847-54, (2015) Mango fruit contain many bioactive compounds, some of which are transcription factor regulators. Estrogen receptor alpha (ERα) and beta (ERβ) are two regulators of gene transcription that are important in a variety of physiological processes and also in disea... |
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Simultaneous ultrasound-assisted water extraction and β-cyclodextrin encapsulation of polyphenols from Mangifera indica stem bark in counteracting TNFα-induced endothelial dysfunction.
Nat. Prod. Res. 29 , 1657-63, (2015) This study proposes an alternative technique to prevent heat degradation induced by classic procedures of bioactive compound extraction, comparing classical maceration/decoction in hot water of polyphenols from Mango (Mangifera indica L.) (MI) with ultrasound... |
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Mangiferin inhibits endoplasmic reticulum stress-associated thioredoxin-interacting protein/NLRP3 inflammasome activation with regulation of AMPK in endothelial cells.
Metab. Clin. Exp. 64(3) , 428-37, (2015) Endothelial dysfunction is tightly associated with cardiovascular complications in diabetic patients. This study aims to investigate the effects of mangiferin on the regulation of endothelial homeostasis under endoplasmic reticulum stress (ER stress) conditio... |
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Chitosan-based luminescent/magnetic hybrid nanogels for insulin delivery, cell imaging, and antidiabetic research of dietary supplements.
Int. J. Pharm. 427(2) , 400-9, (2012) In this work, the chitosan-based luminescent/magnetic (CLM) nanomaterials were synthesized by direct gelation of chitosan, CdTe and superparamagnetic iron oxide into the hybrid nanogels. The morphology, sizes and properties of the nanogels prepared with diffe... |
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Increased absorption of mangiferin in the gastrointestinal tract and its mechanism of action by absorption enhancers in rats.
Drug Dev. Ind. Pharm. 39(9) , 1408-13, (2013) The therapeutic efficiency of mangiferin is restricted by its low intestinal permeability. In order to improve the oral absorption of mangiferin, potential of enhancers, including TPGS, sodium deoxycholate and Carbopol 974P, were investigated in a series of i... |