乙基磺酸
乙基磺酸结构式
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常用名 | 乙基磺酸 | 英文名 | Ethanesulfonic acid |
|---|---|---|---|---|
| CAS号 | 594-45-6 | 分子量 | 110.132 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 394.9±0.0 °C at 760 mmHg | |
| 分子式 | C2H6O3S | 熔点 | −17 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | >230 °F | |
| 符号 |
GHS05, GHS07 |
信号词 | Danger |
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Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells.
Drug Des. Devel. Ther. 9 , 425-64, (2015) Ovarian cancer is a leading killer of women, and no cure for advanced ovarian cancer is available. Alisertib (ALS), a selective Aurora kinase A (AURKA) inhibitor, has shown potent anticancer effects, and is under clinical investigation for the treatment of ad... |
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Novel in silico-designed estradiol analogues are cytotoxic to a multidrug-resistant cell line at nanomolar concentrations.
Cancer Chemother. Pharmacol. 75(2) , 431-7, (2015) 2-Methoxyestradiol (2ME) is a promising anti-cancer agent that disrupts the integrity and dynamics of the spindle network. In order to overcome the pharmacokinetic constraints of this compound, a panel of sulphamoylated estradiol analogues were in silico-desi... |
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Polyoxometalates--potent and selective ecto-nucleotidase inhibitors.
Biochem. Pharmacol. 93(2) , 171-81, (2015) Polyoxometalates (POMs) are inorganic cluster metal complexes that possess versatile biological activities, including antibacterial, anticancer, antidiabetic, and antiviral effects. Their mechanisms of action at the molecular level are largely unknown. Howeve... |
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Inhibition of STAT5a by Naa10p contributes to decreased breast cancer metastasis.
Carcinogenesis 35(10) , 2244-53, (2014) N-α-Acetyltransferase 10 protein (Naa10p, also called arrest-defective 1), the catalytic subunit of N-acetyltransferase A, is a critical regulator of cell death and proliferation. Naa10p is also shown to regulate cancer metastasis by inhibiting cell motility;... |
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Characterizing the structure of lipodisq nanoparticles for membrane protein spectroscopic studies.
Biochim. Biophys. Acta 1848(1 Pt B) , 329-33, (2015) Membrane protein spectroscopic studies are challenging due to the difficulty introduced in preparing homogenous and functional hydrophobic proteins incorporated into a lipid bilayer system. Traditional membrane mimics such as micelles or liposomes have proved... |
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Olanzapine inhibits proliferation, migration and anchorage-independent growth in human glioblastoma cell lines and enhances temozolomide's antiproliferative effect.
J. Neurooncol. 122(1) , 21-33, (2015) The poor prognosis of patients with glioblastoma fuels the search for more effective therapeutic compounds. We previously hypothesised that the neuroleptic olanzapine may enhance antineoplastic effects of temozolomide the standard chemotherapeutic agent used ... |
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Nutritional values and bioactive components of under-utilised vegetables consumed by indigenous people in Malaysia.
J. Sci. Food Agric. 95 , 2704-11, (2015) Diverse plants species in the forest remain under-utilised and they are mainly consumed only by local people. However, increasing issues in food security prompted the present study, which explores the nutritional and antioxidant aspects of Malaysian under-uti... |
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Antitumor activity of the MEK inhibitor TAK-733 against melanoma cell lines and patient-derived tumor explants.
Mol. Cancer Ther. 14(2) , 317-25, (2015) The goal of this study was to investigate the activity of the selective MEK1/2 inhibitor TAK-733 in both melanoma cell lines and patient-derived melanoma xenograft models. In vitro cell proliferation assays using the sulforhodamine B assay were conducted to d... |
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Ag(I)-coordinated hairpin DNA for homogenous electronic monitoring of hepatitis C virus accompanying isothermal cycling signal amplification strategy.
Biosens. Bioelectron. 73 , 195-201, (2015) This work designs a new homogenous electronic monitoring platform for sensitive detection of hepatitis C virus (HCV) on an immobilization-free Ag(I)-assisted hairpin DNA through the cytosine-Ag(+)-cytosine coordination chemistry. The assay consists of target-... |
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Multi-allele genotyping platform for the simultaneous detection of mutations in the Wilson disease related ATP7B gene.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 1006 , 201-8, (2015) Wilson's disease is an inherited disorder of copper transport in the hepatocytes with a wide range of genotype and phenotype characteristics. Mutations in the ATP7B gene are responsible for the disease. Approximately, over 500 mutations in the ATP7B gene have... |