4-氨基苄基磷酸二乙酯
4-氨基苄基磷酸二乙酯结构式
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常用名 | 4-氨基苄基磷酸二乙酯 | 英文名 | diethyl 4-aminobenzylphosphonate |
|---|---|---|---|---|
| CAS号 | 20074-79-7 | 分子量 | 243.23900 | |
| 密度 | 1.153g/cm3 | 沸点 | 383.3ºC at 760mmHg | |
| 分子式 | C11H18NO3P | 熔点 | 90-94 °C(lit.) | |
| MSDS | 美版 | 闪点 | 185.6ºC |
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Aromatic phosphonates inhibit the lysophospholipase D activity of autotaxin.
Bioorg. Med. Chem. Lett. 21 , 5098-101, (2011) Autotaxin (ATX) is an attractive target for the anticancer therapeutics that inhibits angiogenesis, invasion and migration. ATX is an extracellular lysophospholipase D that hydrolyzes lysophosphatidylcholine to form the bioactive lipid lysophosphatidic acid. ... |
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