![]() diethyl 4-aminobenzylphosphonate structure
|
Common Name | diethyl 4-aminobenzylphosphonate | ||
---|---|---|---|---|
CAS Number | 20074-79-7 | Molecular Weight | 243.23900 | |
Density | 1.153g/cm3 | Boiling Point | 383.3ºC at 760mmHg | |
Molecular Formula | C11H18NO3P | Melting Point | 90-94 °C(lit.) | |
MSDS | USA | Flash Point | 185.6ºC |
Aromatic phosphonates inhibit the lysophospholipase D activity of autotaxin.
Bioorg. Med. Chem. Lett. 21 , 5098-101, (2011) Autotaxin (ATX) is an attractive target for the anticancer therapeutics that inhibits angiogenesis, invasion and migration. ATX is an extracellular lysophospholipase D that hydrolyzes lysophosphatidylcholine to form the bioactive lipid lysophosphatidic acid. ... |
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