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醋氨酚-D4

醋氨酚-D4结构式
醋氨酚-D4结构式
品牌特惠专场
常用名 醋氨酚-D4 英文名 Acetaminophen-D4
CAS号 64315-36-2 分子量 155.18700
密度 N/A 沸点 N/A
分子式 C8H5D4NO2 熔点 169-171°C (dec.)
MSDS 中文版 美版 闪点 9℃
符号 GHS07
GHS07
信号词 Warning

In vitro metabolism and drug-drug interaction potential of UTL-5g, a novel chemo- and radioprotective agent.

Drug Metab. Dispos. 42(12) , 2058-67, (2014)

N-(2,4-dichlorophenyl)-5-methyl-1,2-oxazole-3-carboxamide (UTL-5g), a potential chemo- and radioprotective agent, acts as a prodrug requiring bioactivation to the active metabolite 5-methylisoxazole-3-carboxylic acid (ISOX). UTL-5g hydrolysis to ISOX and 2,4-...

Upcyte Human Hepatocytes: a Potent In Vitro Tool for the Prediction of Hepatic Clearance of Metabolically Stable Compounds.

Drug Metab. Dispos. 44 , 435-44, (2016)

In vitro models based on primary human hepatocytes (PHH) have been advanced for clearance (CL) prediction of metabolically stable compounds, representing state-of-the-art assay systems for drug discovery and development. Yet, limited cell availability and lar...

Cytochrome P450 induction response in tethered spheroids as a three-dimensional human hepatocyte in vitro model.

J. Appl. Toxicol. 36 , 320-9, (2016)

Cytochrome P450 (CYP) induction is a key risk factor of clinical drug-drug interactions that has to be mitigated in the early phases of drug discovery. Three-dimensional (3D) cultures of hepatocytes in vitro have recently emerged as a potentially better platf...

Fast determination of 40 drugs in water using large volume direct injection liquid chromatography-tandem mass spectrometry.

Talanta 131 , 719-27, (2014)

This work describes a rapid analytical method based on direct sample injection of water samples for the simultaneous identification/quantification of 40 emerging compounds, including pharmaceuticals and drugs of abuse. The water samples were analyzed by ultra...

Simultaneous attenuation of pharmaceuticals, organic matter, and nutrients in wastewater effluent through managed aquifer recharge: Batch and column studies.

Chemosphere 143 , 135-41, (2015)

Batch and column experiments were conducted to evaluate the removal of organic matter, nutrients, and pharmaceuticals and to identify the removal mechanisms of the target contaminants. The sands used in the experiments were obtained from the Youngsan River lo...