![]() (4S,4aR,7S,7aR,12bS,13S)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9,13-triol结构式
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常用名 | (4S,4aR,7S,7aR,12bS,13S)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9,13-triol | 英文名 | (4S,4aR,7S,7aR,12bS,13S)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9,13-triol |
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CAS号 | 131563-73-0 | 分子量 | 301.33700 | |
密度 | 1.54g/cm3 | 沸点 | 537.2ºC at 760mmHg | |
分子式 | C17H19NO4 | 熔点 | N/A | |
MSDS | N/A | 闪点 | 278.7ºC | |
符号 |
![]() ![]() ![]() GHS02, GHS06, GHS08 |
信号词 | Danger |
Impurities in a morphine sulfate drug product identified as 5-(hydroxymethyl)-2-furfural, 10-hydroxymorphine and 10-oxomorphine.
J. Pharm. Sci. 92(3) , 485-93, (2003) Stability testing of morphine sulfate formulated with nonpareil sugar seeds (consisting of sucrose and starch) and fumaric acid revealed the formation of the three impurities 5-(hydroxymethyl)-2-furfural, 10-hydroxymorphine and 10-oxomorphine. 5-(Hydroxymethy... |
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Morphine impurity with opioid activity is identified as 10 alpha-hydroxymorphine.
Pharm. Res. 7(11) , 1205-7, (1990)
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Separation of morphine and its oxidation products by capillary zone electrophoresis.
J. Pharm. Biomed. Anal. 20(1-2) , 179-83, (1999) Separation of morphine and its oxidation products (10-S-hydroxymorphine, pseudomorphine and morphine N-oxide) by capillary zone electrophoresis in Tris-borate buffer in the presence of cyclodextrins was studied. Pyridoxine was used as an internal standard. |
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