1,3-二羧甲基-2-甲基-2-硫代异脲
1,3-二羧甲基-2-甲基-2-硫代异脲结构式
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常用名 | 1,3-二羧甲基-2-甲基-2-硫代异脲 | 英文名 | 1,3-Bis(methoxycarbonyl)-2-methyl-2-thiopseudoeura |
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| CAS号 | 34840-23-8 | 分子量 | 206.220 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | N/A | |
| 分子式 | C6H10N2O4S | 熔点 | 102-105ºC(lit.) | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
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CYP2J2 and CYP2C19 are the major enzymes responsible for metabolism of albendazole and fenbendazole in human liver microsomes and recombinant P450 assay systems.
Antimicrob. Agents Chemother. 57(11) , 5448-56, (2013) Albendazole and fenbendazole are broad-spectrum anthelmintics that undergo extensive metabolism to form hydroxyl and sulfoxide metabolites. Although CYP3A and flavin-containing monooxygenase have been implicated in sulfoxide metabolite formation, the enzymes ... |
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Design, synthesis, and biological evaluation of classical and nonclassical 2-amino-4-oxo-5-substituted-6-methylpyrrolo [3, 2-d] pyrimidines as dual thymidylate synthase and dihydrofolate Gangjee A, et al.
J. Med. Chem. 51(1) , 68-76, (2007)
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