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一般危化品
氙结构式
氙结构式
常用名 英文名 xenon
CAS号 7440-63-3 分子量 131.29300
密度 3.52(-109ºC) 沸点 -108.1ºC
分子式 Xe 熔点 -111.8ºC
MSDS 中文版 美版 闪点 N/A
符号 GHS04
GHS04
信号词 Warning

Inhibition of voltage-gated calcium channels as common mode of action for (mixtures of) distinct classes of insecticides.

Toxicol. Sci. 141(1) , 103-11, (2014)

Humans are exposed to distinct structural classes of insecticides with different neurotoxic modes of action. Because calcium homeostasis is essential for proper neuronal function and development, we investigated the effects of insecticides from different clas...

Inhalation anaesthesia: from diethyl ether to xenon.

Handbook of Experimental Pharmacology (182) , 121-42, (2008)

Modern anaesthesia is said to have began with the successful demonstration of ether anaesthesia by William Morton in October 1846, even though anaesthesia with nitrous oxide had been used in dentistry 2 years before. Anaesthesia with ether, nitrous oxide and ...

[Xenon and sevoflurane anti stress activity comparative assessment during elective anaesthesia in pediatric patients].

Anesteziol. Reanimatol. (1) , 7-10, (2013)

Research objective was to compare Xenon and Sevoflurane anti stress activities during elective anaesthesia in Pediatric patients.The results of anaesthesia in 42 patients in age from 1 to 18 years were analyzed. The clinical sings, BIS-index, Somatotropinum h...

Biophysical changes induced by xenon on phospholipid bilayers.

Biochim. Biophys. Acta 1828(5) , 1347-56, (2013)

Structural and dynamic changes in cell membrane properties induced by xenon, a volatile anesthetic molecule, may affect the function of membrane-mediated proteins, providing a hypothesis for the mechanism of general anesthetic action. Here, we use molecular d...

In vivo imaging of reactive oxygen and nitrogen species in murine colitis.

Inflamm. Bowel Dis. 20(8) , 1435-47, (2014)

Traditional techniques analyzing mouse colitis are invasive, laborious, or indirect. Development of in vivo imaging techniques for specific colitis processes would be useful for monitoring disease progression and/or treatment effectiveness. The aim was to eva...

Crystallographic studies with xenon and nitrous oxide provide evidence for protein-dependent processes in the mechanisms of general anesthesia.

Anesthesiology 121(5) , 1018-27, (2014)

The mechanisms by which general anesthetics, including xenon and nitrous oxide, act are only beginning to be discovered. However, structural approaches revealed weak but specific protein-gas interactions.To improve knowledge, we performed x-ray crystallograph...

Silencing the KCNK9 potassium channel (TASK-3) gene disturbs mitochondrial function, causes mitochondrial depolarization, and induces apoptosis of human melanoma cells.

Arch. Dermatol. Res. 306(10) , 885-902, (2014)

TASK-3 (KCNK9 or K2P9.1) channels are thought to promote proliferation and/or survival of malignantly transformed cells, most likely by increasing their hypoxia tolerance. Based on our previous results that suggested mitochondrial expression of TASK-3 channel...

Mitochondrial impairment observed in fibroblasts from South African Parkinson’s disease patients withparkinmutations

Biochem. Biophys. Res. Commun. 447(2) , 334-40, (2014)

• Mitochondrial dysfunction observed in patients with parkin-null mutations. • Mitochondrial ATP levels were decreased. • Electron-dense vacuoles were observed in the patients. • Mitochondria from muscle biopsies appeared within normal limits. • One patient d...

Elastic scattering spectroscopy as an optical marker of inflammatory bowel disease activity and subtypes.

Inflamm. Bowel Dis. 20(6) , 1029-36, (2014)

In 10% to 15% of individuals, inflammatory bowel disease (IBD) is difficult to classify as ulcerative colitis (UC) or Crohn's disease (CD). Previous work has demonstrated that probe-based elastic scattering spectroscopy (ESS) can produce spectra, informed by ...

Comparison of the effects of xenon and sevoflurane anaesthesia on leucocyte function in surgical patients: a randomized trial.

Br. J. Anaesth. 112(2) , 272-80, (2014)

While most anaesthetics are known to suppress immune reactions, data from experimental studies indicate the enhancement of reactivity to inflammatory stimulators under xenon treatment. We investigated the effect of xenon anaesthesia on leucocyte function in s...